Question : How the Karyotype of Iymphocytes was prepared by Tjio and Levan?Edit How the Karyotype of Iymphocytes was prepared by Tjio

Question : How the Karyotype of Iymphocytes was prepared by Tjio and L

1.	Question : How the Karyotype of Iymphocytes was prepared by Tjio and Levan?Edit How the Karyotype of Iymphocytes was prepared by Tjio
Answer» Solution :Preparation of Karyotype Tjio and Levan (1960) described a SIMPLE method of culturing lymphocytes from the human blood. Mitosis is induced followed by addition of colchicine to ARREST cell DIVISION at metaphase STAGE and the suitable spread of metaphase chromosomes is photographed. The individual chromosome are cut from the photograph and are arranged in an orderly fashion in homologous pairs. This arrangement is called a karyotype. Chromosome banding PERMITS structural definition and differentiation of chromosomes.