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Question : Role of Y-chromosome is crucial for maleness - Justify.

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Solution :Current analysis of Y chromosomes has REVEALED numerous genes and regions with potential genetic function, some genes with or without homologous counterparts are seen on the X. Present at both ends of the Y CHROMOSOME are the pseudoautosomal regions (PARs) that are similar with regions on the X chromosome which SYNAPSE and recombine during meiosis. The remaining 95% of the Y chromosome is referred as the Non-combining Region of the Y (NRY). The NRY is divided equally into functional genes ( euchromatic) and non-functional genes (heterochromatic). Within the euchromatin regions, is a gene CALLED Sex determining region Y (SRY). In humans, absence of Y chromosome invitably leads to female development and this SRY gene is ABSENT in X chromosome. The gene product of SRY is the testes determining factor (TDF) present in the adult male testis.


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