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Read the passage carefully and select the best answer to each question out of the given four alternatives.Malnutrition affects millions of people worldwide and is responsible for one-fifth of deaths in children under the age of five. Children can also experience impairedcognitive development and stunted growth.According to Finlay and UBC PhD student Er ic Brown, malnutrition can be difficult to treat because it affects the good bacteria that live in the gut. People sufferingfrom malnutrition often show signs of a disease known as environmental enteropathy, which is an inflammatory disorder of the small intestine and is likely caused byingesting pathogenic fecal bacteria early in life from a contaminated environment. This shifts the balance of the original healthy bacteria in the gut and leads to poorabsorption of nutrients.The study, published in Nature Communications, explains how the research team developed a mouse model to reproduce the symptoms of environmentalenteropathy and malnourishment.“We were able to see how a malno urished diet has a strong, measurable impact on the microbes in the small intestine,” said Brown. “This new model gives us theopportunity to examine the impact of malnutrition on gut microbiology and assess the role of infections.”Pathogenic bacterial infections like salmonella and E. coli are huge problems in developing countries beca use they are much more harmful to people suffering frommalnutrition, leading to chronic diarrhea and inflammation.“Treatments and vaccines created in developed nations and tested on healthy people often don't work in malnourished populations,” said Finlay, distinguishedprofessor at UBC's Peter Wall Institute for Advanced Studies. “People suffering from malnutrition respond differently.”With an animal model, Finlay said researchers will be better able to test treatments and understand how malnutrition impacts a child's development.According to the passage, what has a strong impact on the microbes in the small intestine?1). Malnourished diet2).Salmonella3).E. coli4). Vitamin C |
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