Red cell formation is increased A. By giving vitamin B12 injections

1.	Red cell formation is increased A. By giving vitamin B12 injections to healthy people on a normal diet. B. In blood donors one week after a blood donation. C. In patients with haemolytic anaemia. D. By giving injections of erythropoietin to nephrectomized patients. E. In patients who have a raised blood reticulocyte count.
Answer» A. False Healthy normal people do not benefit from vitamin B₁₂supplements. B. True The RBC deficit is corrected by bone marrow stimulation by erythropoietin. C. True The reduced oxygen carrying capacity of the blood causes release of erythropoietin which stimulates RBC stem cells in the bone marrow. D. True The anaemia seen in nephrectomized patients is due largely to lack of erythropoietin. E. True A raised reticulocyte count is evidence of a hyperactive bone marrow.

Red cell formation is increased A. By giving vitamin B12 injections to healthy people on a normal diet. B. In blood donors one week after a blood donation. C. In patients with haemolytic anaemia. D. By giving injections of erythropoietin to nephrectomized patients. E. In patients who have a raised blood reticulocyte count.

Answer»

A. False Healthy normal people do not benefit from vitamin B₁₂supplements.

B. True The RBC deficit is corrected by bone marrow stimulation by erythropoietin.

C. True The reduced oxygen carrying capacity of the blood causes release of erythropoietin which stimulates RBC stem cells in the bone marrow.

D. True The anaemia seen in nephrectomized patients is due largely to lack of erythropoietin.

E. True A raised reticulocyte count is evidence of a hyperactive bone marrow.

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