(i) Addictive Effects: Most of these substances have addictive effects, thus create physical and psychological dependence. Its regular use becomes the need of athletes to perform well in physical activity. ‘ 

(ii) Cardiac Problems : Doping has adverse effect over heart and causes many types of cardiac problems like varied heartbeat, high blood pressure, hypertension, cardiac arrest, heart attack, etc.’ 

(iii) Affects Kidney and Liver : Doping substance is strong chemical, thus it adversely affects kidney and liver. It leads to non-functioning or partial damage or failure of these important organs. Many times it is also the cause of cancer in the body. 

(iv) Unbalanced Psychological Behaviour: These substances, usually lead to unbalanced psychological behaviour like aggression, loss of concentration, dizziness, headache, loss of neuromuscular responses, nausea feeling, nervousness, high anxiety, insomnia, depression etc. 

(v) Musculature Body: Anabolic steroid causes strong muscles, thus affects the feminine look of females like musculature body of females, loss of hair (baldness), male voice, causes beard or moustaches on face, etc., thus personality is affected.