1.

The pH of 0.005 M codeine (C_18H_21NO_3) solution is 9.95 . Calculate its ionization constant and pK_b.

Answer»

Solution :Calculation of concentrationof `OH^-` :
pH=-log `[H^+]`= 9.95
So, pOH=(14.0-9.95)=4.05
pOH=-log `[OH^-]` =4.05 = `bar5.95`
`therefore [OH^-]`=-Antilog `(bar5.95)`
`[OH^-]=10^(-4.05) = 8.9125xx10^(-5)`
pH = 9.95 `gt` 7.0, So codeine is weak BASE. So, ionic EQUILIBRIUM is as under :
`{:(,C_18H_21NO_(3(aq))+H_2O_((L)) hArr, C_18H_21NO_3H_((aq))^(+) + , OH_((aq))^(-)),("INITIAL concen.", 0.005 M,0.0 M, 0.0M),("Change in equilibrium:",0.005 M ,0.0 M ,0.0 M),("Molarity at equili.",underset(approx0.005 M)(0.005-x),underset(=8.91xx10^(-5))(xM),underset(=8.91xx10^(-5))(x M)):}`
Calculation of `K_a` :
`K_b=([C_18 H_21 NO_3H^+][OH^-])/([C_18H_21NO_3])`
`K_b=((8.9125)^2(10^(-5))^2)/0.005=1.5886xx10^(-6)`
`pK_b=-log (K_b)=-log (1.5886xx10^(-6))`
=-(0.2010-6.0)=-(-5.799)=+ 5.799 `APPROX` 5.8


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