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The pH value of gasfric juice in humna stomach is about 1.8 and in intiestine , it is about 7.8. The `pk_(a)` value of aspirin is 3.5 Aspirin will beA. completely ionised in the small intestine and in the stomachB. unionised in the small intestine and in the stomachC. unionised in the small intestine and almost unionised In the stomachD. ionised the stomach and almost unionised in the small intestine |
Answer» Correct Answer - C Aspirin, is a moderate acid `(pK_1= 3.5)`, hence is almost unionised in stomach due to strong acidic medium of it (because of HCI), this is due to common ion effect. While in small intestine, the medium is alkaline, hence, aspirin will be sufficiently ionised in small intestine. |
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