What are monocolonal antibodies? Write down their characteristics.

1.	What are monocolonal antibodies? Write down their characteristics.
Answer» In 1970, Georges Kohler and Cesar Milstein developed the technique of producing monoclonal antibodies by fusing normal anibody producing cells with cells from cancerous tumours. Their main characteristics are: (i) Monoclonal antibodies are pure and highly specific for specific antigens. (ii) These can be easily cultured outside the body. (iii) These antibodies are more effective and ideal for diagnosis of specific diseases. Their most effective clinical application is immune suppression for kidney transplantation.

Answer»

In 1970, Georges Kohler and Cesar Milstein developed the technique of producing monoclonal antibodies by fusing normal anibody producing cells with cells from cancerous tumours. Their main characteristics are:

(i) Monoclonal antibodies are pure and highly specific for specific antigens.

(ii) These can be easily cultured outside the body.

(iii) These antibodies are more effective and ideal for diagnosis of specific diseases.

Their most effective clinical application is immune suppression for kidney transplantation.

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