What Are The Main Advantages And Disadvantages Of Live Attenuated Vac

1.	What Are The Main Advantages And Disadvantages Of Live Attenuated Vaccines As Compared To Killed Vaccines?
Answer» Advantages: induce not only SERUM ANTIBODIES but also cellular immunity and local IGA antibodies. Some may be applied orally. Usually fewer doses are NEEDED. Disadvantages: Attenuated strains may revert to virulent in rare cases. They may cause disease in immunosuppressed patients. Live attenuated microbes are usually heat sensitive and MUST be refrigerated. Advantages: induce not only serum antibodies but also cellular immunity and local IgA antibodies. Some may be applied orally. Usually fewer doses are needed. Disadvantages: Attenuated strains may revert to virulent in rare cases. They may cause disease in immunosuppressed patients. Live attenuated microbes are usually heat sensitive and must be refrigerated.

What Are The Main Advantages And Disadvantages Of Live Attenuated Vaccines As Compared To Killed Vaccines?

Answer»

Advantages: induce not only SERUM ANTIBODIES but also cellular immunity and local IGA antibodies. Some may be applied orally. Usually fewer doses are NEEDED.

Disadvantages: Attenuated strains may revert to virulent in rare cases. They may cause disease in immunosuppressed patients. Live attenuated microbes are usually heat sensitive and MUST be refrigerated.

Advantages: induce not only serum antibodies but also cellular immunity and local IgA antibodies. Some may be applied orally. Usually fewer doses are needed.

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