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What did Meselson and Stahl observe when They cultured E. coli in a medium containing `""^15Nh_4CL` for a few generations and centrifuged the content? they transferred one such bacterium to the normal medium of `NH_4Cl` and cultured for 2 genretion ? What did Meselson and Stahl conclude from this experiment? Explain With the help of diagram Which is the first geretic material? Give reasons in support of your answer.

Answer» Meselson and Stahl obsered that in the E. coli bacterium the DNA becomes completely labelled with `N^15` medium by centrifugation for few genretion
·After two genretion density changed and showed equal amount of light DNA(`N^14`) and dark hybrid DNA `(N^14-N^15)`.
They concluded that DNA replicates semi-conservately.[For Figure See Q. 30. Set-I. Outside Delhi, 2008].
.RNA is the first genetic material.
RNA is highly reactive, and acts as a catalyst as well as genetic material.
Essential life processes such as metabolism, translation and splicing evolved around RNA.


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