1.

What is cause of itai itai disease ?​

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ANSWER:

Itai-itai disease is CAUSED by cadmium (Cd) EXPOSURE, produced as a result of human activities related to industrialisation, and this condition was FIRST recognised in Japan in the 1960s. 1 2. Itai-itai disease is characterised by osteomalaecia with severe BONE pain and is associated with renal tubular dysfunction.

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