What is DNA probe ? – InterviewSolution

InterviewSolution

1.	What is DNA probe ?
Answer» DNA Probe : It is a solution of radioactive, single-stranded DNA or oligodeoxy nucleotides (a DNA segment of few to several nucleotide’s). The name probe signifies the fact that this DNA molecule is used to detect and identify the DNA fragment in the gel membrane that has a sequence complementary to the probe. The probe hybridizes with the complementary DNA on the membrane to the greater extent with a low non-specific binding on the membrane. This step is known as hybridization reaction.

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