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What is oxidative decarboxylation? What is its significance for Kreb's cycle?

Answer»

Oxidative decarboxylation: Pyruvic acid in molecules enter in the mitochondria where each of them is converted into two carbon atoms-acetic acid. One carbon is released as CO2. The removal of carbon dioxide from pyruvic acid is called decarboxylation. 

Oxidative decarboxylation plays very significant role in Kreb's cycle. This step is called link reaction or transition reaction or gateway step as it links glycolysis with Krebs cycle.



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