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What is Rh factor? What is its significance?

Answer»

This factor is a protein which is composed of about 417 amino acids. Blood groups are categorized as Rh positive or negative on the basis of presence or absence of Rh factor respectively. Rh factor matching is also important for blood transfusion. If Rh positive blood is transfused to an Rh negative person then recipient’s body produces IgG antibodies. These antibodies destroy RBCs by agglutination. This results in increased levels of bilirubin in blood which adveresely affects the liver and spleen. As a result, the person dies due to renal failure.



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