When a nucleophile attach te carbonyl group of a carboxylic acid deriative, the carbon-oxygen pi- bond breaks. The resulting intermediate is called a tetrahedral inntermediuate because sp^(2) carbon in the reactant has become a tetrahedral (sp^(3)) carbon in the intermediate. Here overset(..)Y^(ɵ) is leaving gourp, the weaker base is expelled preferentially. Q. Consider the following reaction: CH_(3)-underset(O^(18))underset(||)C-overset(18)C^(ɵ) (2). CH_(3)-underset(O)underset(||)C-C^(ɵ) (3). CH_(3)CH_(2)OH (4). CH_(3)CH_(2)overset(18)(O)H

When a nucleophile attach te carbonyl group of a carboxylic acid der

1.	When a nucleophile attach te carbonyl group of a carboxylic acid deriative, the carbon-oxygen pi- bond breaks. The resulting intermediate is called a tetrahedral inntermediuate because sp^(2) carbon in the reactant has become a tetrahedral (sp^(3)) carbon in the intermediate. Here overset(..)Y^(ɵ) is leaving gourp, the weaker base is expelled preferentially. Q. Consider the following reaction: CH_(3)-underset(O^(18))underset(\|\|)C-overset(18)C^(ɵ) (2). CH_(3)-underset(O)underset(\|\|)C-C^(ɵ) (3). CH_(3)CH_(2)OH (4). CH_(3)CH_(2)overset(18)(O)H
Answer» (1 and 4) only (2) (1 and 3) only (4) SOLUTION :