1.

Which base, ammonia (NH3) or triethylamine [(CH3CH2)3N], would be more effective to use for the following conversion?

Answer»

Triethylamine. Amines can be nucleophiles or bases. Increasing their steric bulk near the nitrogen atom diminishes their nucleophilicity while retaining the basicity. Since the substrate is sterically accessible to nucleophilic attack, a bulky base is needed to promote elimination.



Discussion

No Comment Found

Related InterviewSolutions