1.

Which of the following first binds to the NLS protein sequence?(a) Importin-alpha(b) Importin-beta(c) CAS protein(d) NLS detecting protein

Answer» Correct option is (a) Importin-alpha

Easiest explanation: The molecules that contain Nucleus Localization Signal (NLS) sequence, are immediately ushered into the nucleus through nucleopore. The first step of this transport involves binding of importin-alpha to the NLS sequence, which then acts as a bridge for the attachment of importin-beta.


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