1.

Which of the following hormones can play a significant role in osteoporesis ?(1) Aldosterone and Prolactin(2) Progesterone and Aldosterone(3) Estrogen and Parathyroid hormone(4) Parathyroid hormone and Prolactin

Answer»

The correct option is(3) Estrogen and Parathyroid hormone

Explanation:

Estrogen and parathyroid hormone can play a significant role in osteoporosis. It is caused due to the deficiency of estrogen and excessive activity of parathormones. Estrogen helps to promote the activity of osteoblast (helps in the formation of bone cells) and inhibits osteoclast (destruct the bones). On the other hand, parathormone promotes the mobilisation of calcium from bones into blood hence causes demineralisation.

The other listed hormones also contribute to osteoporosis but their effects are insignificant or very less. e.g.. low level of progesterone and aldosterone causes bone ]oss whereas raised level of prolactin has been linked with osteoporosis.



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