1.

Which of the following statements regarding the structure of proinsulin and mature insulin are not correct ? (i) Proinsulin is made up of three polypeptide chains -A,B and C (ii) c- polypeptide chain with 33 amino acids is removed prior to insulin formation (iii) Mature insulin is made up of 51 amino acids arranged in two polypeptide chain -A and B (iv) Polypeptide chain A has 30 amino acids and polypeptide chain B has 21 amino acids (v) Polypeptide chains A and B are interconnected by only one S-S linkage.A. (i) and (ii)B. (iii) and (iv)C. (iv) and (v)D. (iii),(iv) and (v)

Answer» Correct Answer - A
Human insulion is made up of of 51 amino acids arranged in two polypeptide chains : A, having 21 amono acids and B, with 30 amino acids. The two polypeptide chains are interconnected by two disulphide bridges


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