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Which of the following steps during glycolysis is associated with utilisation of ATP?A. Glucose `rarr` Glucose -6-phosphateB. Fructose-6-phosphate `rarr` Fructose-1,6-biphosphateC. PEP `rarr` Pyruvic acidD. Both (a) and (b) |
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Answer» Correct Answer - D In the initial phase (energy spendling phase) of glycolysis, the hexoses (i.e., glucose and fructose) ar phosphorylated in a reaction that uses ATP at two steps : First in the conversion of glucose into glucose-6-phosphate and second in the conversion of fructose-6-phophaste to fructose-1,6-biphosphate. These reactions are catalysed by the hexokinase and phospho-fructokinase respectively `"Glucose + ATP" underset(Mg^(2+))overset("hexokinase")(rarr) "Glucose-6-phosphate + ADP"` `"Fructose-6-phosphate + ATP" underset(Mg^(2+))overset("Phosphofructokinase")(rarr) "Fructose-1,6-biphosphate + ADP"` |
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