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Why does not formaldehyde take part in aldol condensation?

Answer» Aldol condensation involvses the nucleophile attrack to carbanion generated by one molecular of a particular carbonyl `3*5`). In case the medium is srongly acidic (`p_(H)` close to `1`). then the ammonia derivates will be also protonated and will not be able to act as a nucleophile.


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