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1.

Match each disease with its correct type of vacinne A. `{:(,(A),(B),(C),(D)),(,(iv),(iii),(ii),(i)):}`B. `{:(,(A),(B),(C),(D)),(,(ii),(i),(iii),(iv)):}`C. `{:(,(A),(B),(C),(D)),(,(iii),(ii),(iv),(i)):}`D. `{:(,(A),(B),(C),(D)),(,(i),(ii),(iv),(iii)):}`

Answer» Correct Answer - A
2.

ADA deficiency results in:A. chromosomal disordersB. increased risk of infertilityC. decrease in the yield of crop plantsD. inability of the immune system to function normally

Answer» Correct Answer - D
3.

What is released in body during disease which results in fever?A. PyrogensB. AntibodiesC. InterferonsD. Interleukins

Answer» Correct Answer - A
4.

Excessive and inappropriate immune response to an antigen is:A. allergyB. anaphylaxisC. multiple sclerosisD. immune deficiency

Answer» Correct Answer - A
5.

Cornea transplant in humans is almost never rejected.This is becauseA. it has no blood supplyB. it is a non-living layerC. it is composed of enucleated cellsD. its cells are least penetrable by bacteria

Answer» Correct Answer - A
6.

Assertion . Mast cells in human body release excessive amount of inflammatory chemicals which cause allergic reactions. Reason . Allergens in the environment on reaching human body stimulates mast cells in certain individualsA. Both (A) and (R) are true and (R) is the correct explana-tion of (A)B. Both (A) and (R) are true but (R) is not the correct explanation of (A)C. (A) is true but (R) is falseD. Both (A) and (R) are false

Answer» Correct Answer - A
7.

Consider the following four statements (i-iv) regarding kidney transplant and select the two correct ones out of these (i) Even if a kidney transplant is proper the recipient may need to take immuno-suppressants for a long time (ii) The cell-mediated immune response is responsible for the graft rejection (iii) The B-lumphocytes are responsible for rejection of the graft (iv) The acceptance or rejection of a kidney transplant depends on specific interferons The correct statements areA. 1 and 2B. 1 and 3C. 2 and 3D. 3 and 4

Answer» Correct Answer - A
8.

One of the inflammatory reactions induced by histmines is:A. vasodilation of peripheral blood vasselsB. vasoconstriction of blood vasselsC. increased vascular permeabilityD. accelerated blood clotting

Answer» Correct Answer - A
9.

T-Lymphocytes originate fromA. liverB. thymusC. bone marrowD. none of these

Answer» Correct Answer - B
10.

A transplant between individuals of the same species, but with different MHC/HLA alleles is:A. isograftB. allograftC. autograftD. xenograft

Answer» Correct Answer - B
11.

The cells involved in inflammatory reactions areA. BasophilsB. MonocytesC. neutrophilsD. Macrophage

Answer» Correct Answer - A
12.

The location where B-lymphocytes differentiate and mature is in the:A. bone marrowB. bursa of FabriciusC. both (a) and (b)D. thymus

Answer» Correct Answer - C
13.

B-lymphocytes are: 1. formed in bone marrow 2. preprocessed in bone marrow 3. preprocessed in liver 4. formed in thymusA. 1,2 and 3 are correctB. 1 and 2 are correctC. 2 and 4 are correctD. 1 and 3 are correct

Answer» Correct Answer - D
14.

Kupffer cells in the liver are involved in:A. pinocytosisB. phagocytosisC. blood clottingD. antibody production

Answer» Correct Answer - B
15.

Macrophages are also known as:A. B-cellsB. Tumour cellC. PhagocytesD. Natural killer cells

Answer» Correct Answer - C
16.

Natural killer lymphocytes are an example for:A. physical barrierB. cytokine barrierC. physiological barrierD. anatomical barriers

Answer» Correct Answer - B
17.

Given: 1. Kupffer cells , 2. T-lymphocytes 3. B-lymphocytes , 4. Megakaryocytes Of the above tissue macrophages are:A. 1 onlyB. 1, 2 and 3 onlyC. 1,2,3 and 4D. 4 only

Answer» Correct Answer - A
18.

When a person dies after stung by a bee followed by the administration of penicillin, death may be due to:A. prophylacitc shockB. anaphylactic shockC. autoimmunityD. sedation

Answer» Correct Answer - B
19.

Which of the following is true for antibodies?A. They kill only virusesB. They are produced by T-cellsC. They are composed of carbohydratesD. They are also known as immunoglobulins

Answer» Correct Answer - D
20.

Antibodies are:A. sugarsB. vitaminsC. albuminsD. `gamma`-globulins

Answer» Correct Answer - D
21.

Which one of the following acts as a physiological barrier to the entry of microorganisms in human bodyA. SkinB. TearsC. MonocytesD. Epithelium of urinogenital tract

Answer» Correct Answer - B
22.

In Myasthenia gravis acetylcholineA. esterase activity is inhibitedB. receptors on motor end plate are reducedC. secretion from nerve terminals is reducedD. secretion from nerve terminals is enhanced

Answer» Correct Answer - B
23.

Interferons areA. Antiviral proteinsB. biotic proteinsC. cancer proteinsD. nucleo proteins

Answer» Correct Answer - A
24.

Which cell of immune system cause pore formation at the surface of the plasma membraneA. B-cellB. Killer T-cellC. Helper T-cellD. Suppressor T-cell

Answer» Correct Answer - B
25.

In anaphylactic shock, a substance is released which causes dilation of the blood vessels and capillary leaking. What is this substance called?A. AlbuminB. BenadrylC. HistamineD. Adrenaline

Answer» Correct Answer - C
26.

Recognition and digestion by the phagocytes due to the coated surface of antigens by the antibodies, is known asA. OpsonizationB. ImmunizationC. T-cell immunizationD. B-cell immunization

Answer» Correct Answer - A
27.

Immunoglobulin present in sebum is:A. IgAB. IgEC. IgGD. IgM

Answer» Correct Answer - A
28.

Antigenic determinant sites bind to which portions of an antibody molecule? 1. Light chain , 2. Heavy chain 3. Intermediate chains , 4. Plasma cellsA. 1 and 2 are correctB. 2 and 4 are correctC. 1 and 3 are correctD. 1,2 and 3 are correct

Answer» Correct Answer - A
29.

How many polypeptide chains are present in gamma immunoglobulin or How many variable segments are present in the basic structure of antibody moleculeA. OneB. TwoC. FourD. Three

Answer» Correct Answer - C
30.

How many polypeptide chains are present in gamma immunoglobulin or How many variable segments are present in the basic structure of antibody moleculeA. 6B. 2C. 5D. 4

Answer» Correct Answer - D
31.

The type of immunoglobulin whose function is possible antigen recognition by B-cells may be:A. IgAB. IgDC. IgED. IgG

Answer» Correct Answer - B
32.

The immunoglobulin disulfides do not join:A. light chains with heavy chainsB. two heavy chainsC. two light chainsD. all the above

Answer» Correct Answer - C
33.

Monoclonal antibodies are used for:A. growth inductionB. treatment of breast cancerC. suppression of symptoms of rabiesD. immune suppression for kidney transplantation

Answer» Correct Answer - D
34.

Monoclonal antibodies are produced from hybrid cells, called hybridomas. The cells employed to obtain these hybridoma cells are:A. B-lymphocytes and myeloma cellsB. T-lymphocytes and myeloma cellsC. B- lymphocytes and carcinoma cellsD. Lymphoma cells and bone marrow cells

Answer» Correct Answer - A
35.

Which immunoglobulin is the largest in sizeA. IgAB. IgDC. IgED. IgM

Answer» Correct Answer - D
36.

Which of the following act as antigens, but do not induce antibody production?A. HaustraB. HistonesC. HaptensD. none of these

Answer» Correct Answer - C
37.

Antibody formation and immunity production by globulin protein is found in:A. plasmaB. blood plateletsC. cytoplasm of RBCsD. haemoglobin of RBCs

Answer» Correct Answer - A
38.

The antibacterial protein present in human tears is:A. opsinB. retineneC. LysozymeD. transduction

Answer» Correct Answer - C
39.

Which of the following vaccines are injected to babies at the age of `1(1)/(2), 2(1)/(2)` and `3(1)/(2)` monthsA. Polio and BCGB. DTP-Hib and PolioC. BCG and DTP-HibD. BCG and hepatitis-B

Answer» Correct Answer - B
40.

For the first six months of its life, a child depends on anti-bodies:A. received through foodB. obtained from its motherC. acquired from the environmentD. produced from its immune system

Answer» Correct Answer - B
41.

Which of the following T-cells are destroyed by HIV?A. Cytotoxic T-cellsB. Killer T-cellC. Suppressor T-cellsD. Helper T-cells

Answer» Correct Answer - D
42.

Which of the following disease is due to an allergic reactionA. GoitreB. Skin cancerC. Hay feverD. Enteric fever

Answer» Correct Answer - C
43.

Inflammatory response includes:A. painB. itchingC. swellingD. all of these

Answer» Correct Answer - D
44.

Inflammatory response in allergy is caused by:A. antigensB. antibodiesC. histaminesD. prothrombin

Answer» Correct Answer - C
45.

Which of the following cells guard against the overpro- duction of antibodies?A. Cytotoxic T-cellsB. Helper T-cellsC. Suppressor T-cellsD. none of these

Answer» Correct Answer - C
46.

Antibodies against germs are formed in:A. blood by plateletsB. liver by Kupffer cellsC. blood by plasma cellsD. thymus by lymphocytes

Answer» Correct Answer - C
47.

Which of the following cytoplasmic granules contain hista-mine?A. BasophilsB. NeutrophilsC. both (a) and (b)D. none of these

Answer» Correct Answer - A
48.

Antigen binds to antibody. This binding is result of:A. covalent bondsB. amide formationC. disulphide bridgesD. electrostatic interactions

Answer» Correct Answer - D
49.

Antigen binding site in an antibody is found between:A. two light chainsB. two heavy chainsC. one heavy and one light chainD. either between two light chains or between on heavy and one light chain depending upon the nature of antigen

Answer» Correct Answer - C
50.

Gamma immunoglobulins are synthesized inside:A. liverB. kidneyC. bone marrowD. lymph and lymphoid tissues

Answer» Correct Answer - D