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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 101. |
Genetic engineering has helped in production ofA. thyroxineB. insulinC. parathormoneD. epinephrine |
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Answer» Correct Answer - B Genctic engineering has helped in porduction of insulin |
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| 102. |
production of human protein in bacteria by genetic engineering is possible becacuseA. human chromosomes replicate in bacterial cellB. mechanism of gene regulation is identical in humans nd bacteriaC. bacteria cell can undertake RNA spicingD. genetic code is universal |
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Answer» Correct Answer - D Produciton of human protein in bacteria byu genetic engineerign is possible because genetic code is universal |
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| 103. |
ELISA which is a molecular diagnosis technique is based on the which principle? |
| Answer» Correct Answer - Antigen antibody interaction | |
| 104. |
Which part of the tabacco plant is infected by meloidogyne incognita?A. stemB. rootC. flowerD. leaf |
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Answer» Correct Answer - B Root of the tobacco plant is infected by meloidogyne incognita |
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| 105. |
Which of the following is commolnly used as a vector for introducing a DNA fragement in human lymhocytes?A. retrovirusB. ti plasmidC. `lambda` phage `pBR 322D. |
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Answer» Correct Answer - A Retrovirus is commonly used as a vector for introdcuting a DNA fragement in human lymphocytes |
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| 106. |
Which of the following Bt crops is being growth in india by the farmers?A. brinjalB. soyabeanC. maizeD. cotton |
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Answer» Correct Answer - D Bt cotton is being grown in india by the farmers |
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| 107. |
Which vector is used to replace defective gene in gene therapyA. adenovirusB. cosmidC. ri plasmidD. ti plasmid |
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Answer» Correct Answer - A Adenovirus is used to replace the defective gene therapy |
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| 108. |
RNA interference is usefull forA. micropropagationB. cell defenceC. cell proliferationD. cel differentiation |
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Answer» Correct Answer - B RNA interference is usefull for cell defecne |
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| 109. |
RNA interference involvesA. synthesis of cDNA and RNA using reverse transcriptaseB. silencing of specific mRNA due to complementary RNAC. interference of RNA in synthesis of DNAD. synthesis of mRNA from DNA |
| Answer» Correct Answer - B | |
| 110. |
RNA interference involvesA. synthesis fo cDNA and RNA using reserve transcriptaseB. silencing of specific mRNA in due to coplementary RNAC. Interference of RNA systhesis of DNAD. Synthesis of mRNA from DNA |
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Answer» Correct Answer - B RNA interfernce involves silencing of specific mRNA in due ot compleentaryt RNA |
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| 111. |
A novel strategy was adopted to prevent the infection of nematode was based on which process? |
| Answer» Correct Answer - RNA interference (RNA) | |
| 112. |
The first human hormone produced by recombinant DNA technology isA. progesteroneB. insulinC. estrogenD. thyroxin |
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Answer» Correct Answer - B The first human hormone produced by recombinant DNA technology is insulin |
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| 113. |
Assertion: The recombinant DNA technological processes have made immens impact in the area of healthcare by enabling mass producition of safe and more effective therapeutic drugs Reason: The recombinant therapeutics do not induce unwanted immunological responses as is common in case of similar products isolated from non human sourcesA. If both assertion and reason are true and the reason is the correct explanation of the assertionB. If both assetion and reason are true but reason is not the correct explantion of the assertionC. If assertion is true but reason is falseD. If both assertion and reason are false |
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Answer» Correct Answer - B The recombinant dna techonological processes have made immenes imapact in the area of healthcare by enabling mass lproduction of safe and more efective therapeutic drugs The recombinat therapeutics do not induce unwanted immunlogical reasponses as is common in case of similar products isolated from non human sources |
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| 114. |
For effective treatment of a diseaseA. early diagnosis is required but understanding of its pathophysiology is not requiredB. early diagnosis is not required but understanding of its pathophysiology is requiredC. early diagnosis and understanding of its pathophysiology is requiredD. neither early diagnosis nor understanding of its pathophysiology is required |
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Answer» Correct Answer - C For effective treatment of a disease, early diagnosis and understanding its pathophysiolpogy is very important. Using conventional methods of diagnosis (serum and urine analysis, etc) early detection is not possible, Recombinant DNA technology, Polymerase chain Reaction (PCR) and Enzyme Linked Immuno-sorbent Assay (ELISA) are some of the techniques that serve the purpose of early diagnosis. |
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| 115. |
Gene therapy can be referred to asA. pre-clinical testing for inherited diseases in newbornsB. treatment of diseases caused by genetic defectC. genetic engineering using rDNA technologyD. cancer treatment using in vitro cultured stem cells |
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Answer» Correct Answer - B Correcting of a genetic defect involves delivery of a normal gene into the individual or embryo to take over the function of and compensate for the non-functional gene. |
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| 116. |
Adenosine deaminase deficiency can be permanetly cured by which of the following methods ?A. Bone marrow transplantationB. Enzyme replacement therapyC. Gene therapy at early embryonic stagesD. All of these |
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Answer» Correct Answer - C Adenosine deaminase (ADA) deficiency can be treated by bone marrow transplantion, or by enzyme replacement therapy, in which functiona, ADA is given to the patient by injection. But permanent treatment can be done by introduction of gene isolated from bone marrow cells, which produces ADA, into the cells of the patient at early embryonic stage. |
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| 117. |
Adenosine deaminase enzyme is cruical for which system to function? |
| Answer» Correct Answer - Immune system | |
| 118. |
The organisation which makes decision regarding the validity of GM research and the safety of introducing GM-organisms for public services isA. Genetic Engineering Approval CommitteeB. Genome Environment Action CommitteeC. Genetic Environment Approval CommitteeD. Genetics and Ethical Issue Action Committee |
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Answer» Correct Answer - A Genetic modification of organisms can have unpredictable results when such organisms are introduced into the ecosystem. Therefore, the Indian Government gas set up organisations such as GEAC (Genetic Engineering Approval Committee), Which will make decisions regarding the validity of GM research adn the safety of introducing GM-organisms for public services |
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| 119. |
A monopoly granted to a person who has either invented a new and useful article, made inprovement in an existing article or invented a new process of making an article is calledA. biopiracyB. bioethicsC. patentD. genetic modification |
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Answer» Correct Answer - C A patent is the right granted by government to an inventor to prevent others from commercial use of his invention. When patents are granted for biological entities and for products derived from them, these patents are called biopatents. Primary industrialised countries, like U.S.A Japan and members of European Union, are awarding biopatents. |
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| 120. |
Which technology is used to purify the protein/organic compound ? |
| Answer» Correct Answer - Downstream processing technology | |
| 121. |
Which of the following has not been synthesized by DNA technology?A. InsulinB. HamoglobinC. somostatinD. interferon |
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Answer» Correct Answer - B Haemoglobin has not been synthesized by DNA technology |
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| 122. |
Disorder in which B-lymphocytes and T-lymphocytes are not formed in:A. aidsB. scidC. cystic fibrosisD. musuclar dystrophy |
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Answer» Correct Answer - B Disorder in B lymphocytes ad t lymphocytes are not formed is SCID |
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| 123. |
which of these is used as vector for gene theraphy is scid and gene cloning in higher organisms?A. retrovirusB. enterovirusC. arbovirusD. rotavirus |
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Answer» Correct Answer - A Retrovirus is used as vector for gene therapy is SCID and gene cloning in higher organisms |
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| 124. |
Indentify the correcty match for the given apparatus A. gene guntransfer vectorless direct gene traB. column graph , sepearation of chlorophyll chromatopigmentsC. stirred tank process carry out fermentation bioreactorD. respirometer respiration finding out rate of |
| Answer» Correct Answer - A | |
| 125. |
Find the correct match A. a-1,b-3,c-2,d-1,e-3B. a-2,b-1,c-3,d-1,e-1C. a-3,b-2,c-1,d-3.e-2D. a-2,b-1,c-3,d-1,e-2 |
| Answer» Correct Answer - D | |
| 126. |
Which of the following statements is not correct ?A. Insulin used for diabetic patients was earlier extracted from pancreas of slaughtered cattle and pigs which was more efficient than the genetically engineered insulinB. PCR technique is applied to detect HIV suspected AIDS patients and to detect mutations in genes in suspected cancer patientsC. Bone marrow transplantation requires periodic infusion of genetically engineered lymphocytes in ADA deficient patientsD. Bioremediation is the one of the applications of biotechnology. |
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Answer» Correct Answer - A Earlier, insulin used for curing diabetes used to bee extracted from pancreas of slaughtered pigs and cattle. This insulin was slightly different from human insulin and caused some undersirable side effects such as allergy. Genetically engineered insulin is far more efficient. |
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| 127. |
Assertion : both bacteria and yeasts multiply very fast to form huge polulation which express the desired geneA. correctB. not correctC.D. |
| Answer» Correct Answer - A | |
| 128. |
Bt toxin is produced by a bacterium called_________ . |
| Answer» Correct Answer - Bacillus thuringiensis | |
| 129. |
Which type of gene has been cloned from the bacteria and been expressed in the plant to provide resistance to insects. |
| Answer» Correct Answer - Bt toxin gene | |
| 130. |
Name the orders of insects which killed by proteins that produce by some strains of Bacillus thuringiensis :- |
| Answer» Correct Answer - Lepidopterans, Coleopterans and Dipterans | |
| 131. |
Bt toxin is not toxic to human beings asA. the toxin recognises only insect specific targetsB. bt toxin activation requires temperture above human body temperatureC. bt toxin formation from pro bt state require pH lower than one present in human stomachD. conversation of pro bt to bt state takes place only in highly alkaline condition |
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Answer» Correct Answer - D Bt toxin is not toxic of human beings as conversion of pro bt to bt state takes plae only in highly alkaline conditons |
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| 132. |
Bacillus thuringiensis has been used to kill certain insects such asA. b,cB. a,bC. a,cD. a,b,c |
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Answer» Correct Answer - D Some strains of bacilllus thuringiensis (bt for short) produce proteins that kill certain insects such as: 1 Lepidoternan (tobacco budworm armyworm) 2 coelopterans (beeltes) 3 dipterans(flies , mosquitoes) |
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| 133. |
The Bt toxin is not human beings becauseA. the pro Bt toxin activation requires temperature above human body temperatureB. the Bt toxin recognises only insect-specific targetsC. the pro Bt toxin activation requires pH lower than that present in human stomachD. conversion of pro Bt toxin to Bt toxin takes place in highly alkaline conditions. |
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Answer» Correct Answer - D Conversion of pro Bt toxin to Bt toxin placce in highly alkaline conditions which are not present in human stomach. Human stomach is acidic in nature |
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| 134. |
The critical research area of biotechnology is/areA. downstream processing technologies to purifiy the protein /oprtanic compoundB. providing the best catalyst in the formm of imroved organism usually a microbe or pure enzymeC. creating optimal conditions through engineerign for a catalyst to actD. all of the above |
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Answer» Correct Answer - D There are 3 critical reaserach areas of biotechnology are: 1 providing the best catalyst in the form of imporved organism usually a microbe or pure enzyme 2 creating optimal conditions through engineering for a catalyst to act 3 downstram processing technologies to purify the protein/orgeinic compound |
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| 135. |
The insecticidal protein in Bt cotton is binds to theA. foregut epithelial cellsB. midgut messothelial cellsC. midgut epithelial cellsD. hindgut mesothelial cells |
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Answer» Correct Answer - C The insecticidal protein inbt cotton is binds to the midgut epithelial cells of insects |
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| 136. |
The choice of the Bt tox in genes is depends upon theA. type of the cropB. type of targeted pestC. the type of vectorD. both a and b |
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Answer» Correct Answer - D The choice of the bt toxin genes is depends upon the crop and the targeted pest |
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| 137. |
Study the following statements regarding Bt toxins produced by bacterium Bacillus thuringiensis and select the correct oneA. Most strains of Bacilus thuringiensis produce proteins that kill certain insects such as lepidopterans, coleopterans and dipteransB. Bt toxin proteins do not kill the bacteria themselves because the toxin proteins occur in an inactive from called protoxinsC. When an insect ingests the inactive Bt toxin, it is converted to an active form of toxin due to alkaline pH of the gut which solubilises the protein crystalsD. all of these |
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Answer» Correct Answer - D Soil bacterium, Bacillus thruingiensis (Bt) produces proteins that kill certain insects like lepidopterans (tabacco budworm,armyworm), coleopterans (beetles) and dipterans (flies, mosquitoes). Bacillus thuringiensis forms some intracellular protein crystals. These crystals contain some intracelluar protein. The Bt toxin protein exists as inactive toxin and is converted into an active form due to the alkaline pH of the alimentary canal that solubilises the crystals. The activated toxin binds to the surface of midgut epithelial cells and create pores which cause cell swelling and lysis and finally cause death of the insect. |
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| 138. |
Fill in the Blanks The choice of Bt genes depends upon _______(a)_______and _______(b)_____as most Bt toxins are ____(c)_______ |
| Answer» Correct Answer - (a) The crop (b) the target pest (c) Insect group specific | |
| 139. |
CryllAb and crylAb produce toxins that control A. cotton bollworms and corn borer respectivelyB. corn borer and cotton bollworms respectivelyC. tabacco budworms and nematodes respectivelyD. nematodes and tobacco budworms respectively |
| Answer» Correct Answer - A | |
| 140. |
Bt toxin kills insects byA. inhibiting protein synthesisB. generating excessive heatC. creating pores in the midgut epithelial cells, leading to cell swelling and lysisD. obstructing a biosynthetic pathway |
| Answer» Correct Answer - C | |
| 141. |
Bt toxin genes have been expressed in plante in order to provide resistance against (i) lepidopterans and fungi (ii) aminals and bacteria (iii) bacteria and fungi (iv) coleopterans and diaterans (v) lepidopteransA. (ii) and (iii)B. (i),(ii) and (iv)C. (iii) and (v)D. (iv) and (v) |
| Answer» Correct Answer - D | |
| 142. |
Which of the following statement is true/false Agrochemical based agriculture is a option that can be thought for increasing food production |
| Answer» Correct Answer - True | |
| 143. |
All are the biotechnological applications in order to increase food production exceptA. apicultureB. agro-chemical based agricultureC. organic farmingD. genetically engineered crop-based agriculture |
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Answer» Correct Answer - A Rearing of honeybees for obtaining honey and bee wax is called apiculture. It is not a biotechnological application. |
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| 144. |
A protoxin isA. a primitive toxinB. a denatured toxinC. toxin produced by protozoaD. inactive toxin |
| Answer» Correct Answer - D | |
| 145. |
The trigger for activation of toxin of Bacillus thuringiensis isA. acidic pH of stomachB. high temperatureC. alkaline pH of gutD. mechanical action in the insect gut |
| Answer» Correct Answer - C | |
| 146. |
Form which of the following techniques early detection is not possibleA. b,c and ceB. a and dC. a,d and eD. b and e |
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Answer» Correct Answer - B for effective treatment of a disease early diagnosis and understanding its pahophyssiology is very important using conventional methods of diagnosis (serun and urine analysis etc) early detection is not posible Recombinant DNA technology polymerase chain reaction (PCR) and enzyme linked immuniosrobent assay (elisa) are some of the techniques that sreve the purpose of early diagnosis |
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| 147. |
Which is not a pharmaceutical produce obtained through biotechnologyA. human insulinB. clotting factorC. cholecystokininD. human growht hormone |
| Answer» Correct Answer - C | |
| 148. |
Electroporation procedure involves:A. fast passage of food through sieve pores in phloem elements with the help of electic stimulationB. opening of stomatla pores during night by artifical lightC. making transient pores in the cell membrane to introduce gene constractsD. purification of saline water with the help of a membrane system |
| Answer» Correct Answer - A | |
| 149. |
A doctor while operating on an HIV (+)ve patient accidentally cuts himself with a scalpel. Suspecting himself to have contracted the virus which test will he take to rule out/confirm his suspicion ?A. PCRB. Routine urine examinationC. TLCD. DLC |
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Answer» Correct Answer - A Very low count of bacteria or viruses (when the symptoms of the disease are not yet visible) cab be detected by multiplication of their nucletic acid by PCR (PCR can detect very low amounts of DNA). PCR is usually used to detect HIV in suspected AIDS patients. |
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| 150. |
In the following table identify the correct matching of the crop its decrease and the corresponding pathogen |
| Answer» Correct Answer - A | |