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551.

Veronal and luminal are derivatives of barbituric acid which are ......A. TranquillizersB. Non-narcotic analgesicC. Antiallergic drugsD. Neurologically active drugs

Answer» Correct Answer - A::D
Veronal and luminal are neither antiallergic nor non-narcotic analgesics.
552.

Veronal and luminal are derivatives of barbituric acid which are ______A. tranquilizersB. non-narcotic analgesicC. antiallergic drugsD. neurologically active drugs

Answer» Correct Answer - A::D
Veronal and luminal are neither non-narcotic analgesic nor antiallergic drugs.
553.

Synthetic tranquillisers are mostly barbituric acid derivatives (e.g. veronal, luminal, seconal, amytal and nembutal). Other tranquillisers which are not barbituric acid derivatives are chlordiazepoxide, equanil meprobamate, valium (diazepam), etc. Opium alkaloids such as morphine and codeine are powerful analgesics (reduce pain). Heroin which is morphine diacetate is a widely used narcotic analgesic. Drugs which are used to cure diseases caused by microbes are called antimicrobials. These may be either sulpha drugs such as sulphapyridine, sulphadiazine, sulphaguanidine or they may be antibiotics. Antibiotics such as erythromycin, tetracycline, chloramphenicol which inhibit or arrest the growth of microbes are called bacteriostatic while others which kill the microbes are called bactericidal antibiotics. Which of the following tranquillisers is not a derivative of barbituric acid ?A. VeronalB. EquanilC. SeconalD. Luminal

Answer» Correct Answer - B
554.

Synthetic tranquillisers are mostly barbituric acid derivatives (e.g. veronal, luminal, seconal, amytal and nembutal). Other tranquillisers which are not barbituric acid derivatives are chlordiazepoxide, equanil meprobamate, valium (diazepam), etc. Opium alkaloids such as morphine and codeine are powerful analgesics (reduce pain). Heroin which is morphine diacetate is a widely used narcotic analgesic. Drugs which are used to cure diseases caused by microbes are called antimicrobials. These may be either sulpha drugs such as sulphapyridine, sulphadiazine, sulphaguanidine or they may be antibiotics. Antibiotics such as erythromycin, tetracycline, chloramphenicol which inhibit or arrest the growth of microbes are called bacteriostatic while others which kill the microbes are called bactericidal antibiotics. The bactericidal and bacteriostatic antibiotics respectively areA. Penicillin, ofloxacinB. Erythromycin, tetracyclineC. Penicillin, chloramphenicolD. Tetracycline and penicillin

Answer» Correct Answer - C
555.

Synthetic tranquillisers are mostly barbituric acid derivatives (e.g. veronal, luminal, seconal, amytal and nembutal). Other tranquillisers which are not barbituric acid derivatives are chlordiazepoxide, equanil meprobamate, valium (diazepam), etc. Opium alkaloids such as morphine and codeine are powerful analgesics (reduce pain). Heroin which is morphine diacetate is a widely used narcotic analgesic. Drugs which are used to cure diseases caused by microbes are called antimicrobials. These may be either sulpha drugs such as sulphapyridine, sulphadiazine, sulphaguanidine or they may be antibiotics. Antibiotics such as erythromycin, tetracycline, chloramphenicol which inhibit or arrest the growth of microbes are called bacteriostatic while others which kill the microbes are called bactericidal antibiotics. Which of the following is/are antibacterials ?A. PenicillinB. SulphapyridineC. OfloxacinD. All

Answer» Correct Answer - D
556.

Synthetic tranquillisers are mostly barbituric acid derivatives (e.g. veronal, luminal, seconal, amytal and nembutal). Other tranquillisers which are not barbituric acid derivatives are chlordiazepoxide, equanil meprobamate, valium (diazepam), etc. Opium alkaloids such as morphine and codeine are powerful analgesics (reduce pain). Heroin which is morphine diacetate is a widely used narcotic analgesic. Drugs which are used to cure diseases caused by microbes are called antimicrobials. These may be either sulpha drugs such as sulphapyridine, sulphadiazine, sulphaguanidine or they may be antibiotics. Antibiotics such as erythromycin, tetracycline, chloramphenicol which inhibit or arrest the growth of microbes are called bacteriostatic while others which kill the microbes are called bactericidal antibiotics. Among the following the narcotic analgesic isA. heroinB. ibuprofenC. naproxenD. aspirin

Answer» Correct Answer - A
557.

Veronal, a barbiturate drug, is used asA. antioxidantB. sadativeC. antisecpticD. antibiotics

Answer» Correct Answer - B
558.

A substance which can act both as an antiseptic and disinfectant is :A. phenolB. Iodine abd iodoformC. DettolD. Bithional and 1% phenol

Answer» Correct Answer - A
559.

Which is mismatched regarding the examples ?A. Broad spectrum Antibiotic - ChloramphenicolB. Narrow spectrum antibiotic - AmpicillinC. Antiseptic -FuracineD. Antifertility -Novestrol

Answer» Correct Answer - B
560.

Birth control pills essentially containsA. Synthetic estrogenB. Synthetic progesteroneC. Both (1) & (2)D. Neither (1) nor (2)

Answer» Correct Answer - C
561.

Birth control pills contain a mixture ofA. Aspirin + IbuprofenB. Luminal + EquanilC. Norethindrone + EthynylestradiolD. Cimetidine + Brompheniramine

Answer» Correct Answer - c
562.

Which is the correct statement about birth control pills?A. Contain estogen onlyB. Contain progesterone onlyC. Contain a mixture of estrogen and progesterone derivativesD. Progesterone enhances ovulation.

Answer» Correct Answer - C
Birth control pills contain a mixture of estrogen and progesterone derivatives .
563.

Which is the correct statement about birth control pills?A. Contain estrogen onlyB. Contain progesterone onlyC. Contain a mixture of estrogen and progesterone derivativesD. Progesterone enhances ovulation

Answer» Correct Answer - C
Chemical substances which are used to check pregnancy in women are called birth control pills. Birth control pills essentially contain a mixture of synthetic estrogen and progesterone dierivatives, both these are sex hormones. It is known that progesterone suppresses ovulation and estrogen control the menstrual cycle.
Some of the commonly used pills contain a mixture of norethindrone (a progesterone derivative) and novestrol (an estrogen).
564.

Assertion (A) Penicillin (G) is an antihistamine. Reason (R) Penicillin (G) is effective against gram positive as well as gram negative bacteria.A. If both assertion and reason are true and reason is the correct explanation of assertion .B. If both assertion and reason are true but reason is not the correct explanation of assertion .C. If assertion is true but reason is false.D. If both assertion and reason are false.

Answer» Correct Answer - D
Penicillin (G) is an antibiotic and is effective against some gram positive bacteria.
565.

Assertion (A) Penicillin (G) is an antihistamine. Reason (R) Penicillin (G) is effective against gram positive as well as gram negative bacteria.A. Assertion and reason both are correct statements but reason does not explain assertion.B. Assertion and reason both are correct and reason explains the assertion.C. Both assertion and reason are wrong statements.D. Assertion is correct statement reason is wrong statement.

Answer» Correct Answer - C
Both assertion and reason are wrong statements. Correct assertion Penicillin (G) is an antibiotic.
Correct reason Penicillin is effective against some gram positive bacteria.
566.

Which of the following statements are incorrect about penicillin ?A. An abtibacterial fungusB. Ampicillin is its synthetic modificationC. It has bacteriostatic effectD. It is a broad spectrum antibiotic

Answer» Correct Answer - C::D
Penicillin is a group of anibiotics derived From Penicillium fungi. Ampicillin and Amoxycillin are synthetic modifications of penicillin. Pencillin destroys bacteria by destroying the cell wall of the microorganism or kill the bacteria so. It has bacteriocidal effect.
Penicillin as a class of antibiotics are generally narrow spectrum but when used in the combination with other antibiotics, it can make up a part of broad spectrum antibiotis.
567.

Molecular formula of cimetidine isA. `C_(13)H_(22)N_(4)O_(3)S`B. `C_(10)H_(14)N_(4)S`C. `C_(29)H_(36)O_(2)`D. `C_(29)H_(34)O_(2)`

Answer» Correct Answer - B
568.

Molecular formula of chloramphinicol isA. `C_(10)H_(18)O`B. `C_(8)H_(9)CIO`C. `C_(12)H_(6)CI_(4)O_(2)S`D. `C_(11)H_(12)CI_(2)N_(2)O_(5)`

Answer» Correct Answer - D
569.

Arsenic containing medicine used for tratment of syhillis isA. olfaxacinB. penicillinC. salvarsanD. tetacycline

Answer» Correct Answer - C
570.

Which of the following is a narrow spectrum antibiotic?A. penicillinB. TetracyclineC. AmpicllinD. Amoxycllin

Answer» Correct Answer - A
571.

What is salvarsan?A. An antibioticB. An antifertillity drugC. An antisepticD. An analgesic

Answer» Correct Answer - A
572.

Give an example of a soap and indicate its polar and nonpolar parts.

Answer» Sodium stearate is an example of soap. nonpolar part `to underset"Sodim stearate"((CH_3(CH_2)_16) - COONa larr )` polar part
573.

Which of the following is not an analgesic ?A. IbuprofenB. Dichlofenac sodiumC. NaproxenD. Ofloxacin

Answer» Correct Answer - D
Ofloxation is used as antibiotic .
574.

The most common chemical method to perserve fishes isA. dehydrationB. irradiationC. saltingD. by adding sugar

Answer» Correct Answer - C
575.

Brine is an aqueous solution ofA. aqueous solution of backing sodaB. aqueous solution of boric acidC. aqueous solution of benzoic acidD. aqueous solution of NaCI

Answer» Correct Answer - D
576.

Vinegar containsA. 6 to 10 % valeric acidB. 6 to 10 % valiumC. 6 to 10 % acetic acidD. 6 to 10 % formic acid

Answer» Correct Answer - C
577.

Drug which helps to reduce anxiety and brings about calmnes is :A. tranquilizerB. diureticC. analgesicD. antihistamine

Answer» Correct Answer - A
Drug, which helps to reduce anxiety, and bring about calmess is transquilizer, e.g. phenelzine, ipronialazied etc.
578.

Brine helps in food perservation byA. Killing the germsB. destroying the enzyme actionC. sealing the food with layer of salt and pervent the direct contactD. reducing the avaible water for the growth of microbes

Answer» Correct Answer - D
579.

For sterlization and perservation of squashes which one of the following is used ?A. ChlorineB. 1 % phenolC. `SO^(2)`D. 0.2 % phenol

Answer» Correct Answer - C
580.

With the help of an example explain how do transquilizers control the feeling of depression ?

Answer» Noradrenaline is a neurotransmitter which plays a cruciaal role in mood changes. If somehow any person has low level of noradrenaline in the body, then the signal sending activity becomes slow and the person suffers from depression.
For removing depression and to boost the mood, tranquillizers are used. These drugs inhibit the engyme which catalyst the degradation of noradrenaline.
From this result, neurotransmitter noradrenaline is slowly metabolished and can thus activate the receptor for longer periods.
581.

Which of the following is scientific explanation of depression ?A. An increased level of sugar in the blood leads to depression .B. Low levels of noradrenaline, a neurotransmitter in the blood leads to depression .C. Release of extra gastric juices in the stomach leads to depression.D. Sleep inducing drugs lead to depression.

Answer» Correct Answer - B
Noradrenaline is a neurotransmitter that plays a role in mood swings. Low levels of noradrenaline lower the signal-sending activity and make the person suffers from depression.
582.

Assertion : Detergents with straight chain of hydrocarbons are preferred over branched chain. Reason : Detergents with brached chain hydrocarbon part are expensive.A. If both assertion and reason are true and reason is the correct explanation of assertion .B. If both assertion and reason are true but reason is not the correct explanation of assertion .C. If assertion is true but reason is false.D. If both assertion and reason are false.

Answer» Correct Answer - C
Detergents with branched chain hydrocarbon part are non-biodegradable as bacteria cannot degrade them easily .
583.

What are antibiotics?Give example.

Answer» Antibiotics:The chemical substances produced by micro organisms and inhibit the growth or destroy microoraganisms are called antibiotics.
(Or)
The substance produced totally or partly by chemical synthesis which in low concentration inhibits the growth (or) destroy microorganism by intervening in their metabolic process are called antibiotics.E.g:Penicillin,Chloramphenicol etc.
584.

Why sulpha drugs are not true antibiotics?

Answer» Sulpha drugs inhibit microbial growth but do not kill them, i.e. , these drugs are bacteriostatic in nature. Hence, sulpha drugs are not true antibiotics.
585.

Which of the following are not used as food preservatives ?A. Table saltB. Sodium hydrogen carbonateC. Cane sugarD. Benzoic acid

Answer» Correct Answer - B::C
Sodium hydrogen carbonate and cane sugar are not preservatives.
586.

Which of the following are sulpha drugs?A. SulphapyridineB. ProntosilC. SalvarsanD. Nardil

Answer» Correct Answer - A::B
Salvarsan is an antimicrobial while Nardil is an antidepressant drug.
587.

Which of the following statements is not true about enzyme inhibitors ?A. Inhibit the catalytic activity of the enzymeB. Prevent the binding of substrateC. Generally a strong covalent bond is formed between an inhibitor and an enzymeD. Inhibitors can be competitive or non competitive

Answer» Correct Answer - C
Generally a weak bond such as H-bonding, van der Waals interactions, etc. is formed between the enzyme and the inhibitor.
588.

Tincture of iodin isA. aqueous solution of `I_(2)`B. solution of `I_(2)` in aqueous `KI`C. alcholic solution of `I_(2)`D. aqueous solution of `KI`

Answer» Correct Answer - C
Tinchure of iodine is on alcoholic solution containing about `2.5 I_(2)` and `2.5% KI`, used as an antiseptic.
589.

The active chemical present in lodex which gives relief from pain in sciatica and rheumatism isA. phenyl salicylateB. methyl salicylateC. ethyl salicylateD. salicylic acid

Answer» Correct Answer - D
Methyl salicylate has the general medicinal properties of the salicylates, and is applied either alone or with other analgesics for easing the pain of lumbago, rheumatism and sciatica.
Phenyl salicylate (commonly called solol) is used as an internal antiseptica.
590.

A narrow spectrum antibiotic is active againstA. grams positive or gram negative bacteriaB. gram negative bacteria onlyC. single organism or one diseaseD. both gram positive and gram negative bacteria

Answer» Correct Answer - A
Antibiotics are now defined as chemical substances which in low concentration, either kill or inhibit the growth of microorganisms by intervening in their metabolic processes.
The full range of microorganisms attacked by an antibiotic is called its spectrum.
Broad spectrum antibiotics are effective against several different tupes of harmful bacteria ie., a wide range of gram-positive and gram-negative bacteria. These effective mainly against gram-positive or gram-negative bacteria are narrow spectrum antibiotics.
Chloramphenicol is a broad spectrum antibiotics penicillin-G has narrow spectrum. If an antibiotic is effective against a single organism or diseases then it is limited spectrum antibiotic.
591.

Explain the term target molecules or drug targets as used in medicinal chemistry.

Answer» Drug targets(or)Target molecules:Macro molecules like carbohydrates,lipids,proteins,nuclic acids and enzymes which interact with the drugs are called drug targets (or) Target molecules.
592.

Which of the following is not a target molecule for drug function in body?A. CarbohydratesB. LipidsC. VitaminsD. Proteins

Answer» Correct Answer - C
593.

Which of the following is not a target molecule for drug function in body ?A. CarbohydratesB. LipidsC. VitaminsD. Proteins

Answer» Correct Answer - C
Drugs usually interact with biomolecules such as carbohydrates , lipids, proteins and nucleic acids. These are called target molecules or drug targets .
594.

Which of the following is not a target molecule for drug function in body-A. carbohydratesB. lipidsC. vitaminsD. proteins

Answer» Correct Answer - C
Carbohydrates, proteins, nucleic acids and lipids are target molecules for drug function in the body.
595.

Which is not true about enzyme inhibitors-A. Prevent the binding of substrateB. A strong covalent bond is formed between the inhibitor and enzymeC. These can be competitive or non-competitiveD. Inhibit the catalytic activity of the enzyme

Answer» Correct Answer - B
Inhibitors attach with enzymes covalently but do not from strong bonds.
596.

Which of the following statements is not true about enzyme inhibitors ?A. Inhibit the catalytic activity of the enzyme .B. Prevent the binding of substrate .C. Generally a strong covalent bond is formed between an inhibitor and an enzyme.D. Inhibitors can be competitive or non-competitive .

Answer» Correct Answer - C
Generally a weak bond such as H-bonding , van der Walls interaction etc. is formed between an inhibitor and an enzyme.
597.

Which is not true about enzyme inhibitors-A. inhibit the catalytic activity of the enzymeB. prevent the binding of substrateC. generally a strong covalent bond is formed between an inhibitor and an enzymeD. inhibitors can be competitive or non-competitive

Answer» Correct Answer - C
weak bonds such as H-bond, van der Waals interactions, etc. are found between an inhibitor and an enzyme.
598.

Label the hydrophilic and hydrophobic parts of `CH_3(CH_2)_15overset(o+)N(CH_3)_3Br^(ѳ)`

Answer» `ubrace(CH_3(CH_2)_15)_"Hydrophobic part"- ubrace(overset(o+)N(CH_3)_3Br^(ѳ))_"Hydrophilic part"`
599.

Label the hydrophilic and hydrophobic parts in the following compounds. (a)`CH_3(CH_2)_10CH_2OSO_3^(-)Na^+` , (b)`CH_3(CH_2)_15-overset+N(CH_3)_3Br^-` , (c ) `CH_3(CH_2)_16COO(CH_2CH_2O)_n CH_2CH_2OH`

Answer» (a)`ubrace(CH_3(CH_2)_10CH_2)_"Hydrophobic"-ubrace(OSO_3^(-)Na^(+))_"Hydrophilic part"`
(b)`ubrace(CH_3(CH_2)_15)_"Hydrophobic part"-ubrace(overset+N(CH_3)_3Br^-)_"Hydrophilic part"`
(c )`ubrace(CH_3(CH_2)_16)_"Hydrophobic part"-ubrace(COO(CH_2CH_2O)_nCH_2CH_2OH)_"Hydrophilic acid"`