InterviewSolution

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51.	What is the name of the interaction made by the immune system?(a) Permanent(b) Transient(c) Active(d) PassiveThis question was posed to me in examination.This interesting question is from Cell Interactions topic in section Extracellular Matrix and Cell Interactions of Cell Biology
Answer» Right answer is (b) Transient Best EXPLANATION: The transient or otherwise known as temporary INTERACTIONS are the cell-cell interaction DONE by the IMMUNE system. These are done when there is an INFLAMMATORY reaction.

52.	Which of the following protein is present in large amount in tight junctions?(a) Albumin(b) Globulin(c) Claudin(d) ElastinI got this question in an online interview.My query is from Extracellular Matrix and Cell Interactions in chapter Extracellular Matrix and Cell Interactions of Cell Biology
Answer» Right option is (c) Claudin To explain: The tight junctions contain the PROTEIN claudin in large amount followed by occluding and other proteins. The tight junctions are USEFUL in the TRANSPORT of materials.

53.	What is S- layer?(a) Solid layer(b) Surface layer(c) Secondary layer(d) Soluble layerThis question was addressed to me in exam.I'm obligated to ask this question of Extracellular Matrix and Cell Interactions in division Extracellular Matrix and Cell Interactions of Cell Biology
Answer» The correct CHOICE is (b) SURFACE layer To EXPLAIN: The S-layer is otherwise known as a surface layer. It is present in the cell wall of most of the ARCHAEA bacteria. This layer is composed of proteins and glycoproteins. They are about a thickness of 5 to 25nm.

54.	In an immunoglobulin, the heavy chains and the light chains are held together by ____________(a) Diphosphate bond(b) Dichloride bond(c) Disulphide bond(d) Dihydroxide bondThis question was addressed to me in final exam.This is a very interesting question from Extracellular Matrix and Cell Interactions topic in division Extracellular Matrix and Cell Interactions of Cell Biology
Answer» RIGHT ANSWER is (c) Disulphide bond Best explanation: The immunoglobulin has TWO chains, the light chain and the heavy chain. Two light chains and two heavy chains are HELD TOGETHER by disulphide bond.

55.	What is the use of matrix-bound nanovesicles?(a) Enzyme technology(b) Tissue engineering(c) Biofuel production(d) Pharma product productionI had been asked this question by my college professor while I was bunking the class.I'd like to ask this question from Interaction of Cells with Extracellular Matrix topic in portion Extracellular Matrix and Cell Interactions of Cell Biology
Answer» Correct answer is (b) Tissue ENGINEERING The explanation: Matrix-bound nanovesicles are used in the field of tissue engineering for surgical needs. They can be used to produce ARTIFICIAL tissues for esophagus, BREAST, tendon, ETC.

56.	Which of the following is used by cells to interact with other cells?(a) Cell junctions(b) Cell adhesions(c) Cell detectors(d) Cell tubulesThe question was posed to me in a national level competition.This key question is from Cell Interactions in portion Extracellular Matrix and Cell Interactions of Cell Biology
Answer» The CORRECT option is (a) Cell junctions To explain I would SAY: Cell junctions are USED by cells to interact with each other in certain TISSUES. These are stable interactions made for the development and function of the cell.

57.	Which genetic disorder is associated with accumulation of proteoglycans?(a) Polysaccharidoses(b) Mucomonosaccharidoses(c) Mucopolysaccharidoses(d) MonosaccharidosesI had been asked this question by my school principal while I was bunking the class.The origin of the question is Interaction of Cells with Extracellular Matrix in chapter Extracellular Matrix and Cell Interactions of Cell Biology
Answer» CORRECT answer is (c) Mucopolysaccharidoses The explanation: Mucopolysacchaaridoses is a genetic disorder caused by the accumulation of proteoglycans. The LYSOSOMAL CELLS when they are UNABLE to lyse the glycosaminoglycans cause the accumulation of the proteoglycans.

58.	What is present in the cell wall of Mycobacterium tuberculosis?(a) Cellulose(b) Nitric acid(c) Acetone(d) Mycolic acidThis question was addressed to me during an online interview.The question is from Extracellular Matrix and Cell Interactions in chapter Extracellular Matrix and Cell Interactions of Cell Biology
Answer» Correct answer is (d) Mycolic ACID Easy explanation: Mycolic acid is present in the cell wall of Mycobacterium tuberculosis. It was first ISOLATED from this species in the year 1938 by STODOLA et AL. Mycolic acid helps this organism to prevent itself from chemical attacks and dehydration.

59.	Which of the following disease is associated with the disruption of hemidesmosomes?(a) Atherosclerosis(b) Epidermolysis bullosa(c) Myocardial infarction(d) Zellweger syndromeThis question was posed to me in an international level competition.The query is from Interaction of Cells with Extracellular Matrix in chapter Extracellular Matrix and Cell Interactions of Cell Biology
Answer» Right answer is (b) Epidermolysis bullosa To explain I WOULD say: The disruption of hemidesmosomes CAUSE the genetic DISORDER called epidermolysis bullosa. This CAUSES blisters in the skin which can later cause erosions in some parts of the skin.

60.	How many exons do the syndecan have?(a) 3(b) 4(c) 5(d) 6I have been asked this question during an online interview.This interesting question is from Interaction of Cells with Extracellular Matrix topic in section Extracellular Matrix and Cell Interactions of Cell Biology
Answer» Right answer is (c) 5 Best explanation: Syndecans are special proteins which ACTS as a co-receptor in EXTRACELLULAR matrix INTERACTION. These are expressed in a UNIQUE gene and contains 5 EXONS.

61.	Hemidesmosomes are present in keratinocytes.(a) True(b) FalseI had been asked this question at a job interview.The above asked question is from Interaction of Cells with Extracellular Matrix in section Extracellular Matrix and Cell Interactions of Cell Biology
Answer» CORRECT ANSWER is (a) True The BEST explanation: Hemidesmosomes are found in the keratinocytes of the skin which HELPS them attach to the EXTRACELLULAR matrix. These are very much helpful in maintaining the homeostasis of the skin.

62.	What is the key role of fibroblasts?(a) Protecting the cell(b) Producing extracellular matrix(c) Producing lytic enzymes(d) Providing structureI have been asked this question during an interview.My question is from Interaction of Cells with Extracellular Matrix topic in portion Extracellular Matrix and Cell Interactions of Cell Biology
Answer» RIGHT answer is (b) Producing extracellular matrix Best explanation: Fibroblast cells are RESPONSIBLE for producing COLLAGEN and the ECM of the tissues in animals. They synthesize numerous different enzymes and play a key ROLE in wound healing and scab FORMATION.

63.	What is the range of molecular weight of laminins?(a) 400 to 900 kDa(b) 400 to 900 Da(c) 500 to 1000 kDa(d) 500 to 1000 DaI have been asked this question during an internship interview.This intriguing question comes from Interaction of Cells with Extracellular Matrix in section Extracellular Matrix and Cell Interactions of Cell Biology
Answer» The correct OPTION is (a) 400 to 900 kDa Easiest explanation: Laminin is a protein that is USED by CELLS for extracellular matrix interaction. It has a very HIGH molecular weight ranging from 400 to 900 kDa.

64.	What is the key role of Chondroitin sulfate proteoglycans?(a) Extracellular matrix interaction(b) Protection to cell(c) Production of proteins(d) Digesting the toxinsThe question was posed to me in an online interview.My query is from Interaction of Cells with Extracellular Matrix topic in portion Extracellular Matrix and Cell Interactions of Cell Biology
Answer» The correct choice is (a) Extracellular matrix interaction To explain I would say: Proteoglycans are protein substances PRESENT in the extracellular matrix of the cell. Chondroitin sulfate proteoglycans ABBREVIATED as CSPG is WELL KNOWN for its function of extracellular matrix interaction.

65.	Which of the following helps in the attachment of cell to the extracellular matrix?(a) Cell-matrix fusion complex(b) Cell-matrix adhesion complex(c) Cell-matrix substitution complex(d) Cell-matrix addition complexI got this question in an interview for job.This question is from Interaction of Cells with Extracellular Matrix topic in chapter Extracellular Matrix and Cell Interactions of Cell Biology
Answer» The CORRECT ANSWER is (b) Cell-matrix adhesion complex Easy explanation: Cell-matrix adhesion complex shortly known as the CMAC is helpful in the attachment of the cell to the extracellular matrix. This is ALSO aided by SPECIAL proteins called integrins.

66.	The movement of cell with respect to rigidity is called durotaxis.(a) True(b) FalseThe question was posed to me in an interview.This interesting question is from Interaction of Cells with Extracellular Matrix topic in section Extracellular Matrix and Cell Interactions of Cell Biology
Answer» Correct option is (a) True The EXPLANATION is: The CELL migrates towards a greater rigidity in the PROCESS of DUROTAXIS. This is due to the DIFFERENCE in structural properties of the extracellular matrix.