InterviewSolution
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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 51. |
Which of the following is useful in solving cases of parental disputes ?A. ELISAB. Western blottingC. DNA fingerprintingD. Hybridoma technology |
| Answer» Correct Answer - C | |
| 52. |
The pioneer contributor towards the use of human DNA figerprinting in forensic science in India isA. J.C. BoseB. Lalji SinghC. H.KhoranaD. Swaminathan |
| Answer» Correct Answer - B | |
| 53. |
What is it that forms the basis of DNA FingerprintingA. The relative proportions of purines and pyrimidines in DNAB. The relative difference in the DNA occurrence in blood, skin and salivaC. The relative amount of DNA in the ridges and grooves of the fingerprintsD. Satellite DNA occurring as highly repeated short DNA segments |
| Answer» Correct Answer - D | |
| 54. |
Homeotic mutants are mutants in which :A. one structure is replaced by anotherB. one structure is formed in multiple copiesC. the embryo dies during early developmentD. a developing organism resembles to its mother |
| Answer» Correct Answer - A | |
| 55. |
Which of the followings has been investigated as a working model for the study of developmental mutants?A. XenopusB. DrosophilaC. NeurosporaD. Coenorhabditis |
| Answer» Correct Answer - B | |
| 56. |
All eukaryotic genes contain two kinds of base sequences. Which of these plays an important role in protein synthesis?A. ExonsB. IntronsC. Both (a) and (b)D. None of these |
| Answer» Correct Answer - A | |
| 57. |
DNA fingerprintuing method is very useful forA. DNA tests for identity and relationshipsB. Forensic studiesC. PolymorphismD. All of the above |
| Answer» Correct Answer - D | |
| 58. |
When DNA fragments are subjected to an electrical current on a gel, the..........fragments move to the farthest.A. t-RNAB. LargestC. SmallestD. DNA library |
| Answer» Correct Answer - C | |
| 59. |
Which of the following is the best way to determine paternity ?A. Gene countingB. Protein analysisC. DNA fingerprintingD. Chromosome counting |
| Answer» Correct Answer - C | |
| 60. |
In a DNA strand the nucleotides are linked together byA. peptide bondsB. hydrogens bondsC. glycosidicD. phosphodiester bonds |
| Answer» Correct Answer - D | |
| 61. |
Diagram of a nucleosome is given below. Identify A, B and C by selecting the correct option : A. `{:(A,B,D),("Hl Histone",DNA,"Histone octamer"):}`B. `{:(A,B,D),(DNA,"Histone octamer", "Hl Histone"):}`C. `{:(A,B,D),(DNA,"Hl Histone","Histone octamer"):}`D. `{:(A,B,D),("Histone octamer", "Hl Histone","DNA"):}` |
| Answer» Correct Answer - C | |
| 62. |
Which of the following techniques is employes in nucleic acid blotting ?A. ChromatographyB. Gel electrophoresisC. SpectrophotmetryD. Ultracentrifugation |
| Answer» Correct Answer - B | |
| 63. |
Read the following five statements (A to E) about nucleic acids and select the option with all correct statements: (A) DNA is a long polymer of deoxyribonucleotides. (B) The two chains of DNA have anti-parallel polarity. (C) The backbone in a polynucleotide chain is formed due to nitrogenous bases and phosphates. (D) DNA acts as the genetic material in most of the organisms. (E) Uracil is present in RNA at the place of cytosine.A. (A), (D) and (E)B. (B), (C) and (E)C. (A), (C) and (D)D. (A), (B) and (D) |
| Answer» Correct Answer - D | |
| 64. |
the fact that a purine base always pairs through hydrogen bonds with a pyrimidine base in the DNA double helix leads toA. the antiparallel natureB. uniform length in all DNAC. the semiconservative natureD. uniform width throughout DNA |
| Answer» Correct Answer - D | |
| 65. |
The net electric charge on DNA and histones isA. zeroB. both positiveC. both negativeD. negative and positive, respectively |
| Answer» Correct Answer - D | |
| 66. |
Which of the following statements is the most appropriate for sickle cell anaemiaA. It cannot be treated with iron supplements.B. It confers resistance to acquiring malaria.C. It is a molecular diseaseD. All of the above |
| Answer» Correct Answer - D | |
| 67. |
The first genetic material could beA. DNAB. RNAC. ProteinD. Carbohydrates |
| Answer» Correct Answer - B | |
| 68. |
In the operon system, the repressor protein can bind only to the :A. operator geneB. regulator geneC. promoter geneD. structural gene |
| Answer» Correct Answer - A | |
| 69. |
A gene which synthesis a repressor protein is :A. operator geneB. promoter geneC. structural geneD. regulator gene |
|
Answer» Correct Answer - D Regular gene codes for a repressor protein in inducible system and a co-repressor in repressible system. |
|
| 70. |
One of the following is true with respect to AUGA. It codes for methionine onlyB. It is also an initiation codonC. It codes for methionine in both prokaryotes and eukaryotes.D. All of the above |
| Answer» Correct Answer - D | |
| 71. |
The wild type E. coli cells are growing in normal medium with glucose. They are transferred to a medium containing only lactose as sugar. Which of the following changes take place ?A. All operons are inducedB. E. coli cells stop dividingC. The lac operon is inducedD. The lac operon is repressed |
| Answer» Correct Answer - C | |
| 72. |
Lac operon is related with :A. synthesis of lac by lac insectB. synthesis of enzyme of lactose anabolismC. synthesis of enzyme of lactose catabolismD. degradation of lac in the body of lac insect |
| Answer» Correct Answer - C | |
| 73. |
Repressor protein is produced by :A. regulator geneB. operator geneC. structural geneD. promoter gene |
| Answer» Correct Answer - A | |
| 74. |
The sequence of structural genes in lac operon isA. lac A, lac Y, lac ZB. lac A, lac Z, lac YC. lac Y, lac Z, lac AD. lac Z, lac Y, lac A |
| Answer» Correct Answer - D | |
| 75. |
In the lac operon, the structural genes are switched off whenA. repressor binds to the inducerB. repressor binds to the operatorC. repressor binds to the promoterD. repressor binds to the regulator |
| Answer» Correct Answer - B | |
| 76. |
The sequence of genes in lac operon in E. coli is :A. structural genes `rarr` operator gene `rarr` promoter geneB. promoter gene `rarr` operator gene `rarr` structural geneC. structural genes `rarr` promoter gene `rarr` operator geneD. operator gene `rarr` promoter gene `rarr` structural gene |
| Answer» Correct Answer - B | |
| 77. |
Which one of the following statements is incorrect?A. DNA chemically is less reactive and structurally more stable when compared to RNA.B. A nitrogenous base is linked to the pentose sugar through a phosphodiester linkage to form a nucleoside.C. The presence of thymine at the place of uracil confers additional stability to DNA.D. Meselson and Stahl provided experimental evidence for semiconservative DNA replication. |
| Answer» Correct Answer - B | |
| 78. |
Which one of the following is the correct sequence of genes within an operon ?A. Regulator, promoter, operator, structuralB. Regulator, operator, promoter, structuralC. Structural, operator, regulator, promoterD. Promoter, operator, structural, regulator |
| Answer» Correct Answer - A | |
| 79. |
Operon is :A. a set of closely linked genes regulating a metabolic pathways in prokaryotesB. the sequence of three nitrogen bases determining a single amino acidC. the sequence of nitrogen bases in m-RNA which codes for a single amino acidD. a gene responsible for switching on or off other genes |
| Answer» Correct Answer - A | |
| 80. |
The largest gene in man is :A. oncogeneB. dystrophinC. insulin geneD. tumor suppressor gene |
| Answer» Correct Answer - B | |
| 81. |
An environmental agent that triggers transcription from an operon is a/an:A. inducerB. regulatorC. derepressorD. controlling element |
| Answer» Correct Answer - A | |
| 82. |
A functional complex comprising a cluster of genes including structural genes, a promoter gene, an operator region and a regulatory gene was discovered by :A. Jacob and Monod (1961)B. Beadle and Tatum (1958)C. Waston and Crick (1953)D. Britten and Davidson (1969) |
| Answer» Correct Answer - A | |
| 83. |
Gene regulation in prokaryotes was discovered by :A. LederbergB. Beadle and TatumC. Jacob and MonodD. Nirenberg and Mattaei |
| Answer» Correct Answer - C | |
| 84. |
Regulatory proteins are the accessory proteins that interact with RNA polymerase and affect its role in transcription. Which of the following statements is correct about regulatory protein ?A. They only increase expression.B. They only decrease expression.C. They can act both as activators and as repressors.D. They ineract with RNA polymerase but do not affect the expression. |
| Answer» Correct Answer - C | |
| 85. |
In some viruses, DNA is synthesised by using RNA as template . Such a DNA is calledA. c-DNAB. r-DNAC. A-DNAD. B-DNA |
| Answer» Correct Answer - A | |
| 86. |
A short sequence of DNA where the repressor binds, preventing RNA polymerase from attaching to the promoter is called :A. regulatorB. operatorC. promoterD. none of these |
|
Answer» Correct Answer - B When the repressor is bound to the operator, it prevents the RNA polymerase from initiating transcription of the operator. |
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| 87. |
Consider the following statements : A. RNA has evolved from DNA with chemical modification that make it more unstable. B. Central dogma in molecular biology states that the genetic information flows from DNA `rarr` RNA `rarr` Protein. C. In some virsus like tobacco mosaic viruses, QB bacteriophage, DNA is the genetic material. D. Euchromatin is said to be transcriptionally active chromatin, whereas heterochromatin is inactive. Of the above statements :A. B and C are correctB. B and D are correctC. A and B correctD. A and D are correct |
| Answer» Correct Answer - B | |
| 88. |
DNA fingerprints used as evidence in a murder trial look something like supermarket bar codes. The pattern of bars in a DNA fingerprint shows :A. the order of bases in a particular geneB. the order of genes along particular geneC. the exact location of a specific gene in a genomic libraryD. the presence of various-sized fragments from chopped-up DNA |
| Answer» Correct Answer - D | |
| 89. |
Assume you isolate, digest and electrophoresis plasmids from two bacteria. If the resulting DNA fingerprints are identical, this proves the bacteria:A. are relatedB. can hydrolyse x-gelC. contain same plasmidD. are resistant to antibodies |
| Answer» Correct Answer - C | |
| 90. |
Some genes in bacteria and virus mau bcode for more than one polypetide, they are called inA. overlapping genesB. jumping genesC. split genesD. none of these |
| Answer» Correct Answer - A | |
| 91. |
In DNA fingerprinting the process of DNA hybridization with the help of specific DNA probe is described as:A. Western blottingB. Northern blottingC. Southern blottingD. All these methods |
| Answer» Correct Answer - C | |
| 92. |
Alec Jeffreys developed the DNA fingerprinting technique. The probe he used was :A. SNPB. VNTRC. r-DNAD. Ribozyme |
| Answer» Correct Answer - B | |
| 93. |
Which was the last human chromosome to be completely sequenced ?A. Chromosome 1B. Chromosome 11C. Chromosome 21D. Chromosome X |
| Answer» Correct Answer - A | |
| 94. |
What is the first step in the Southern Blot techniqueA. Isolation of DNA from a nucleated cell such as the one from the scene of crimeB. Denaturation of DNA on the gel for hybridization with specific probeC. Production of group of genetically identical cellsD. Digestion of DNA by restriction enzyme |
| Answer» Correct Answer - D | |
| 95. |
RFLPs distributed throughout human genome are useful for :A. Gene mappingB. DNA fingerprintsC. Both (a) and (b)D. None of these |
| Answer» Correct Answer - B | |
| 96. |
The part of m-RNA which removed after transcription by RNA splitting is :A. exonsB. hexaneC. intronsD. none of these |
| Answer» Correct Answer - C | |
| 97. |
Which of the following statements about the t-RNA is not true?A. The secondary structure of t-RNA looks like a clover-leaf.B. The t-RNA has an anticodon loop that has bases complementary to the codon.C. The t-RNAs are specific for each amino acid.D. There are three t-RNAs for stop codons. |
| Answer» Correct Answer - D | |
| 98. |
Protein of gene which is transcribed but not translated isA. exonB. intronC. cistronD. codon |
| Answer» Correct Answer - B | |
| 99. |
Which of the following is the protein-coding gene found in the bithorax complex of Drosophila ?A. UltrabithoraxB. Abdominal AC. Abdominal BD. All of these |
| Answer» Correct Answer - D | |
| 100. |
Which enzyme is used to remove the introns ?A. LigaseB. RibozymeC. ZymozymeD. Carbinozyme |
| Answer» Correct Answer - B | |