InterviewSolution
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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Who gave semiconservative mode of DNA replication for the first time in E. coli with the help of `.^(15) N` heavy nitrogen isotope ?A. Watson and crickB. Kornberg and ochoaC. Meselson and stahlD. Luria and Delbruck |
| Answer» Correct Answer - C | |
| 2. |
The replication of DNA in eukaryotes commences fromA. one end of chromatid extending to the other endB. the centromeres to either of the ends of chromatidsC. several sites along the DNA of the chromatid simultaneouslyD. both ends of the chromatid simultaneously |
| Answer» Correct Answer - C | |
| 3. |
Experiments using N15 (heavy nitrogen) to confirm the semiconserative replication of DNA were carried out byA. Meselson and StahlB. Hershey and ChaseC. Beadle and TautumD. Watson and Crick |
| Answer» Correct Answer - A | |
| 4. |
One-gene-one enzyme hypothesis was proposed by :-A. Linus PaulingB. V IngramC. BrennerD. Beadle and Tautum |
| Answer» Correct Answer - C | |
| 5. |
Formation of polysome does not require `:`A. rRNAB. mRNAC. tRNAD. snRNA |
| Answer» Correct Answer - D | |
| 6. |
If the percentage of A and G is 30% the percentage of T and C isA. 0.4B. 0.7C. 0.3D. 0.5 |
| Answer» Correct Answer - C | |
| 7. |
The DNA coiled in prokaryotes are maintained byA. histoneB. non-histone proteinC. polyaminesD. Both (b) and © |
| Answer» Correct Answer - D | |
| 8. |
Examples of right handed helix is/areA. A and BB. B and ZC. Both (a) and (b)D. None of these |
| Answer» Correct Answer - A | |
| 9. |
Who amongst the following scientists had no contribution in the development of the double helix model for the structure of DNA ?A. Rosalind FranklinB. Maurice wilkinsC. Erwin ChargaffD. Meselson and Stahl |
| Answer» Correct Answer - D | |
| 10. |
In prokaryotes the origin is also calledA. ori CB. ori DC. ori BD. ori A |
| Answer» Correct Answer - A | |
| 11. |
The example of inducible operon isA. trp operonB. lac operonC. Both (a) and (b)D. None of these |
| Answer» Correct Answer - B | |
| 12. |
c-DNA can be formed byA. transaminaseB. DNA ligaseC. RNA dependent DNA polymeraseD. DNA dependent DNA polymerase |
| Answer» Correct Answer - C | |
| 13. |
DNA double helix unwinded by enzymeA. gyraseB. topoisomeraseC. helicaseD. primase |
| Answer» Correct Answer - C | |
| 14. |
Inducible enzyme areA. usually involved in anabolic pathwaysB. produced when a small molecule inactivates the repressor proteinC. produced when an activator molecule enchances the attachment of RNA polymerase with the operatorD. regulated by inherently inactive repressor molecules |
| Answer» Correct Answer - B | |
| 15. |
The enzyme that breaks` H_(2)` bonds in DNA isA. primaseB. topoisomeraseC. DNA polymeraseD. helicase |
| Answer» Correct Answer - D | |
| 16. |
A bacteria containing 100% `N^(15)` nitrogen bases is allowed to replicate in medium containing `N^(14)` bases. After one round of duplication , the result would beA. all individuals would be identical to parentsB. all individual would be radioactive , but the percentage of radioactive in DNA would be 50%C. only 50% individuals would be 50%D. all individuals would be similar to parents , but different among themselves |
| Answer» Correct Answer - B | |
| 17. |
Codes of m-RNA and proteins are `:`A. zig-zagB. coplanerC. colinearD. None of these |
| Answer» Correct Answer - C | |
| 18. |
Protein cannot be a genetic materal because it is notA. large moleculeB. ubiqitosC. having diversity and sepcificityD. able to replicate |
| Answer» Correct Answer - D | |
| 19. |
Sequence of three bases of DNA constitutesA. genomeB. gene poolC. genetic codeD. genetic drift |
| Answer» Correct Answer - C | |
| 20. |
Gene of bacteria and virus code for more than one polypeptide are calledA. Overlapping geneB. Monocistronic geneC. Polycistronic geneD. Non-ambiguous gene |
| Answer» Correct Answer - B | |
| 21. |
Number of RNA molecules present in the spliceosome areA. 4B. 5C. 6D. 7 |
| Answer» Correct Answer - B | |
| 22. |
Exon segments rejoined after splicing byA. DNA primaseB. RNA proteaseC. RNA polymeraseD. RNA ligase |
| Answer» Correct Answer - D | |
| 23. |
Segments of mRNA removed during splicing areA. intronsB. exonsC. promoter regionsD. integrator regions |
| Answer» Correct Answer - A | |
| 24. |
A split gene consist ofA. ExonsB. IntronsC. Both (a) and (b)D. None of these |
| Answer» Correct Answer - C | |
| 25. |
Splicing of RNA depends onA. hnRNAB. exonC. intronD. self-splicing of inton |
| Answer» Correct Answer - A | |
| 26. |
Protein synthesis occurs inA. nucleusB. ribosomeC. cytoplasmD. mitochondria |
| Answer» Correct Answer - B | |
| 27. |
Synthesis of RNA molecule is terminated by a singal recognised byA. `alpha`(alpha) factorB. `beta`-(beta) factorC. `rho` (rho) factorD. `delta` (delta) factor |
| Answer» Correct Answer - C | |
| 28. |
Which of the following is terminated codon?A. AUGB. AUUC. UAGD. UGG |
| Answer» Correct Answer - C | |
| 29. |
Removal of RNA polymerase III from nucleoplasm will affect the synthesis ofA. tRNAB. hnRNAC. mRNAD. rRNA |
|
Answer» Correct Answer - A RNA polymerase III transcribes tRNA ,RNA poly II synthesis mRNA while RNA poly I synthesises rRNA in euksryotes |
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| 30. |
Amino acid sequence in protein synthesis is decided byA. rRNAB. tRNAC. mRNAD. DNA |
| Answer» Correct Answer - C | |
| 31. |
The one aspect which is not a salient feature of genetic code, is its beingA. SpecificB. DegenerateC. AmbiguousD. Universal |
|
Answer» Correct Answer - C The genetic code inside the cell medium is said to be non - ambiguous because a particular codon always codes for the same amino acid |
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| 32. |
The wild type E. coli cells are growing in normal medium with glucose. They are transferred to a medium containing only lactose as sugar. Which of the following changes take place ?A. The lac operon is repressedB. All operon are inducedC. E . Coli cells stop dividingD. The lacs operon is induced |
| Answer» Correct Answer - D | |
| 33. |
This is not produced by E.coli in the lactose medium :A. Lactose dehydrogenaseB. Thicogalactoside transacetylaseC. B-galactosidaseD. Lactose permease |
| Answer» Correct Answer - A | |
| 34. |
In the lac operon system, beta-galactosidase is coded byA. A-geneB. I-geneC. L-geneD. Y-gene |
|
Answer» Correct Answer - D In lac operon system z-gene contains 3063 base pairs and codes for the enzyme `beta`-galactosidase |
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| 35. |
Addition of lactose in a culture of E. coli induces enzymes ---------- to break down the lactose into glucose and galactose.A. `beta`- galactosidase and transacetylaseB. transacetylase and permeaseC. `beta-` galactosidase, permease , transacetylaseD. None of the above |
| Answer» Correct Answer - C | |
| 36. |
The pyrimidines found in RNA areA. cytosineB. uracilC. Both (a) and (b)D. thymine |
| Answer» Correct Answer - C | |
| 37. |
The diagram shows an important concept in the genetic implicatio of DNA. Fill in the blanks A to C. A. A-Translation, B-Transcription, C-Erevin ChargaffB. A-Transcription, B- Translation, C- Francis CrickC. A- Translation, B- Extension, C- Rosalind FranklinD. A- Translation, B- Replication, C- James Watson |
| Answer» Correct Answer - B | |
| 38. |
Which enzyme/s will be produced in a cell in which there is a nonsense mutation in the lac Y gene?A. Lactose permeaseB. TransacetylaseC. Lactose permease and transacetylaseD. `Beta`-galactosidase |
|
Answer» Correct Answer - D If nonsence mutation occurs in lac y gene on that time it forms only z cistron and when z cistron is translated it form `beta` galactosidase |
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| 39. |
The process of translation requiresA. transfer of genetic information from a polymer of nucleotides to a polymer of amino acidsB. splicing , wherethe exons are removed and introns are joined in a defined orderC. a nucleic acid is copied to form amino acidsD. DNA that undergoes copping and tailing |
| Answer» Correct Answer - A | |
| 40. |
The translation step in the process of protein synthesis is made by a charged form ofA. mRNAB. rRNAC. tRNAD. template DNA |
| Answer» Correct Answer - C | |
| 41. |
For initiation of translation, the ribosome first binds toA. mRNAB. rRNAC. hnRNAD. None of thee |
| Answer» Correct Answer - A | |
| 42. |
Which one of the following is wrongly matched?A. Transcription - Writing information from DNA to tRNAB. Translation - Using information in mRNA to make proteinC. Repressor - Binds to operator to stop enzyme protein synthesisD. Operon - Structural genes, operator and promoter |
| Answer» Correct Answer - A | |
| 43. |
Which of the following pairs is correctly matched?A. Ribosomal RNA - Carries amino acids to the site of protein synthesisB. Transcription- Process by which protein is synthesisedC. Translaction- Process by which mRNA carries the informstion from the nucleus to ribosomesD. Anticodon- Site of a tRNA molecule thst binds to the mRNA molecule |
| Answer» Correct Answer - D | |
| 44. |
Which RNA is synthesised by transcription done through the RNA polymerase-II enzymes?A. rRNAB. mRNAC. tRNAD. All of these |
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Answer» Correct Answer - B The RNA polymerase -II enzyme is found in eukaryotic cells it catalyses the transcription of DNA to synthesis precusors of mRNA and most of smRNA and micron RNA |
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| 45. |
Find the wrongly matched pair .A. Har govind khorana - Synthesised RNA molecules chemicallyB. George gamow - Codon is tripletC. Meselson and stahl - Regulation of gene expressionD. Alec jeffreys - DNA fingerprinting |
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Answer» Correct Answer - C Out of the pairs given in the option all pairs the scientist with their discoveries correctly except i.e Meselson and Stahl because they supported the hypothesis that DNA replicates semiconservatively through experiments |
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| 46. |
An eukaryotes, RNA polymerase II transcribes `:`A. hnRNAB. 18S rRNAC. 28S rRNAD. tRNA |
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Answer» Correct Answer - A In nucleus there are three RNA polymerases out of which RNA polymerase II is responsible for the transcription of the mRNA precursoe which is known as hetergeneous nuclear RNA (hnRNA) The process of transcription in eukaryotes is similar to that in the prokaryotes except some additional complexities. |
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| 47. |
If an inheritable mutation is observed in a population at high frequency it is reffered to asA. DNA polymorphismB. Expressed sequence tagC. Sequence annotationD. Linkage |
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Answer» Correct Answer - A In a population if an inheritable mutation is observed at high frequency it is known as DNA polymorphism Polymorphism is the variation in individuals at the genetic level in an inviduals DNA from every tissue i.e blood skin, saliva, hair follicle etc. show the same degree of polymorphism it arises due to mutation and is inherited from parents to children |
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| 48. |
Select the two correct statements out of the four (1-4) given below about lac operon. 1. Glucose or galactose may bind with the repressor and inactivate it 2. In the absence of lactose the repressor binds with the operator region 3. The z-gene codes for permease 4. This was elucidated Francois Jacob and Jacque Monod The correct statements are :A. I and IIB. II and IIIC. III and IVD. IV and I |
| Answer» Correct Answer - A | |
| 49. |
The sequence of structural genes in lac operon isA. Lac A, Lac Y, Lac ZB. Lac A, Lac Z, Lac YC. Lac Y, Lac Z, Lac AD. Lac Z, Lac Y, LacA |
| Answer» Correct Answer - D | |
| 50. |
According to the lac operon concept, which functional unit of the bacterial genetic material is responsible for suppressing the activity of the operator gene in the absence of lactose ?A. Regulator geneB. Structural geneC. Promoter geneD. Repressor protein |
| Answer» Correct Answer - A | |