20 + Interview Questions in GENERAL QA IN ANTIBIOTICS Page 1 InterviewSolution

1.	Which of the following drugs is a gastric acid resistant: a) Penicillin G b) Penicillin V c) Carbenicillin d) Procain penicillin
Answer» b) Penicillin V

Discussion

2.	Antibiotics altering permeability of cell membranes are: a) Glycopeptides b) Polymyxins c) Tetracyclines d) Cephalosporins
Answer» b) Polymyxins

Discussion

3.	Which of the following groups of antibiotics demonstrates a bacteristatic effect: a) Carbapenems b) Macrolides c) Aminoglycosides d) Cephalosporins
Answer» b) Macrolides

Discussion

4.	Lincozamides have the following unwanted effect: a) Nephrotoxicity b) Cancerogenity c) Pseudomembranous colitis d) Irritation of respiratory organs
Answer» c) Pseudomembranous colitis

Discussion

5.	Which of the following groups of antibiotics demonstrates a bactericidal effect? a) Tetracyclines b) Macrolides c) Penicillins d) All of the above
Answer» c) Penicillins

Discussion

6.	Tick the drug belonging to lincozamides:a) Erythromycinb) Lincomycin c) Azithromycin d) Aztreonam
Answer» b) Lincomycin

Discussion

7.	Choose the characteristics of lincozamides: a) Broad-spectum. Demonstrates a bactericidal effect. b) Influence mainly the anaerobic organisms, Gram negative cocci. c) Broad-spectum. Demonstrates a bacteristatic effect.d) Influence mainly the anaerobic organisms, Gram positive cocci.
Answer» d) Influence mainly the anaerobic organisms, Gram positive cocci.

Discussion

8.	Characteristics of Amfotericin B are following, EXCEPT: a) Used for systemic mycosis treatment b) Poor absorption from the gastro-intestinal tract c) Does not demonstrate nephrotoxicity d) Influences the permeability of fungus cell membrane
Answer» c) Does not demonstrate nephrotoxicity

Discussion

9.	Mechanisms of bacterial resistance to anti-microbial agents are the following, EXCEPT: a) Active transport out of a microorganism or/and hydrolysis of an agent via enzymes produced by a microorganism b) Enlarged uptake of the drug by a microorganism c) Modification of a drug’s target d) Reduced uptake by a microorganism
Answer» b) Enlarged uptake of the drug by a microorganism

Discussion

10.	General principles of anti-infective therapy are: a) Clinical judgment of microbiological factors b) Definitive identification of a bacterial infection and the microorganism’s susceptibility c) Optimal route of administration, dose, dosing frequency and duration of treatment d) All of the above
Answer» d) All of the above

Discussion

11.	Rational anti-microbial combination is used to: a) Provide synergism when microorganisms are not effectively eradicated with a single agent alone b) Provide broad coverage c) Prevent the emergence of resistance d) All of the above
Answer» d) All of the above

Discussion

12.	Which of the following drugs is used for systemic and deep mycotic infections treatment: a) Co-trimoxazol b) Griseofulvin c) Amphotericin B d) Nitrofungin
Answer» c) Amphotericin B

Discussion

13.	Which of the following drugs is used for dermatomycosis treatment: a) Nystatin b) Griseofulvin c) Amphotericin B d) Vancomycin
Answer» b) Griseofulvin

Discussion

14.	Antibiotics inhibiting the bacterial cell wall synthesis are: a) Beta-lactam antibiotics b) Tetracyclines c) Aminoglycosides d) Macrolides
Answer» a) Beta-lactam antibiotics

Discussion

15.	Minimal duration of antibacterial treatment usually is: a) Not less than 1 day b) Not less than 5 days c) Not less than 10-14 days d) Not less than 3 weeks
Answer» b) Not less than 5 days

Discussion

16.	All of the following drugs demonstrate a fungicidal effect, EXCEPT: a) Terbinafin b) Amfotericin B c) Ketoconazole d) Myconazol
Answer» b) Amfotericin B

Discussion

17.	Mechanism of Amphotericin B action is: a) Inhibition of cell wall synthesis b) Inhibition of fungal protein synthesis c) Inhibition of DNA synthesis d) Alteration of cell membrane permeability
Answer» d) Alteration of cell membrane permeability

Discussion

18.	Mechanism of penicillins’ antibacterial effect is: a) Inhibition of transpeptidation in the bacterial cell wall b) Inhibition of beta-lactamase in the bacterial cell c) Activation of endogenous proteases, that destroy bacterial cell wall d) Activation of endogenous phospholipases, which leads to alteration of cell membrane permeability
Answer» a) Inhibition of transpeptidation in the bacterial cell wall

Discussion

19.	Pick out the beta-lactamase inhibitor for co-administration with penicillins:a) Clavulanic acid b) Sulbactam c) Tazobactam d) All of the above
Answer» d) All of the above

Discussion

20.	Aminoglycosides have the following unwanted effects: a) Pancytopenia b) Hepatotoxicity c) Ototoxicity, nephrotoxicity d) Irritation of gastrointestinal mucosa
Answer» c) Ototoxicity, nephrotoxicity

Discussion

Explore topic-wise InterviewSolutions in .

Which of the following drugs is a gastric acid resistant: a) Penicillin G b) Penicillin V c) Carbenicillin d) Procain penicillin

Antibiotics altering permeability of cell membranes are: a) Glycopeptides b) Polymyxins c) Tetracyclines d) Cephalosporins

Which of the following groups of antibiotics demonstrates a bacteristatic effect: a) Carbapenems b) Macrolides c) Aminoglycosides d) Cephalosporins

Lincozamides have the following unwanted effect: a) Nephrotoxicity b) Cancerogenity c) Pseudomembranous colitis d) Irritation of respiratory organs

Which of the following groups of antibiotics demonstrates a bactericidal effect? a) Tetracyclines b) Macrolides c) Penicillins d) All of the above

Tick the drug belonging to lincozamides:a) Erythromycinb) Lincomycin c) Azithromycin d) Aztreonam

Choose the characteristics of lincozamides: a) Broad-spectum. Demonstrates a bactericidal effect. b) Influence mainly the anaerobic organisms, Gram negative cocci. c) Broad-spectum. Demonstrates a bacteristatic effect.d) Influence mainly the anaerobic organisms, Gram positive cocci.

Characteristics of Amfotericin B are following, EXCEPT: a) Used for systemic mycosis treatment b) Poor absorption from the gastro-intestinal tract c) Does not demonstrate nephrotoxicity d) Influences the permeability of fungus cell membrane

General principles of anti-infective therapy are: a) Clinical judgment of microbiological factors b) Definitive identification of a bacterial infection and the microorganism’s susceptibility c) Optimal route of administration, dose, dosing frequency and duration of treatment d) All of the above

Rational anti-microbial combination is used to: a) Provide synergism when microorganisms are not effectively eradicated with a single agent alone b) Provide broad coverage c) Prevent the emergence of resistance d) All of the above

Which of the following drugs is used for systemic and deep mycotic infections treatment: a) Co-trimoxazol b) Griseofulvin c) Amphotericin B d) Nitrofungin

Which of the following drugs is used for dermatomycosis treatment: a) Nystatin b) Griseofulvin c) Amphotericin B d) Vancomycin

Antibiotics inhibiting the bacterial cell wall synthesis are: a) Beta-lactam antibiotics b) Tetracyclines c) Aminoglycosides d) Macrolides

Minimal duration of antibacterial treatment usually is: a) Not less than 1 day b) Not less than 5 days c) Not less than 10-14 days d) Not less than 3 weeks

All of the following drugs demonstrate a fungicidal effect, EXCEPT: a) Terbinafin b) Amfotericin B c) Ketoconazole d) Myconazol

Mechanism of Amphotericin B action is: a) Inhibition of cell wall synthesis b) Inhibition of fungal protein synthesis c) Inhibition of DNA synthesis d) Alteration of cell membrane permeability

Pick out the beta-lactamase inhibitor for co-administration with penicillins:a) Clavulanic acid b) Sulbactam c) Tazobactam d) All of the above

Aminoglycosides have the following unwanted effects: a) Pancytopenia b) Hepatotoxicity c) Ototoxicity, nephrotoxicity d) Irritation of gastrointestinal mucosa