InterviewSolution
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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Chromatin is composed of ____________(a) DNA(b) DNA and proteins(c) DNA, RNA and proteins(d) NoneThe question was asked during an internship interview.My doubt stems from The Structure Of Chromosomes topic in chapter Genes and Chromosomes of Biochemistry |
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Answer» The CORRECT ANSWER is (c) DNA, RNA and proteins |
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| 2. |
The extra chromosomal, self-replicating, double stranded, closed, circular DNA molecules are called ____________(a) Viruses(b) Phages(c) Chloroplasts(d) PlasmidsI had been asked this question in exam.My question comes from Chromosomal Elements in division Genes and Chromosomes of Biochemistry |
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Answer» Right choice is (d) PLASMIDS |
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| 3. |
About what proportion of mitochondrial proteins are encoded by nuclear DNA?(a) More than 95%(b) 50%(c) 1%(d) 1.5%This question was addressed to me in quiz.The origin of the question is Chromosomal Elements topic in division Genes and Chromosomes of Biochemistry |
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Answer» RIGHT answer is (a) More than 95% The explanation: More than 95% of mitochondrial PROTEINS are encoded by NUCLEAR DNA. |
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| 4. |
What proportion of the human genome is made up of repetitive DNA sequences?(a) 15%(b) 1%(c) 90%(d) 50%I got this question during an interview for a job.My doubt stems from Chromosomal Elements topic in division Genes and Chromosomes of Biochemistry |
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Answer» RIGHT OPTION is (d) 50% To explain I would say: About half of the human genome is composed of repetitive and non-repetitive DNA SEQUENCES. |
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| 5. |
Which out of the following statements is true about the human genome?(a) The human genome is believed to contain approximately 50,000 protein coding genes(b) All non-protein coding sequences in the genome are believed to be non-functional DNA(c) About 1.6% of the human genome encodes protein sequences(d) Intros are the sections of protein coding genes that actually encode amino acid sequencesThe question was asked by my school principal while I was bunking the class.Question is taken from Chromosomal Elements in section Genes and Chromosomes of Biochemistry |
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Answer» Right option is (c) About 1.6% of the human genome encodes protein sequences |
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| 6. |
The lowest level of chromosome organization is _______________(a) Nucleosome(b) Solenoid(c) 30nm fiber(d) None of theseI have been asked this question in a job interview.Question is taken from Chromosomal Elements topic in division Genes and Chromosomes of Biochemistry |
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Answer» Correct OPTION is (a) Nucleosome |
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| 7. |
How many autosomes are there in humans?(a) 21 pairs(b) 44(c) 46(d) 48I got this question in an internship interview.Query is from Chromosomal Elements in division Genes and Chromosomes of Biochemistry |
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Answer» Correct CHOICE is (b) 44 |
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| 8. |
Under-winding is measured in terms of ____________(a) Supercoiling(b) Linking difference(c) Positive supercoiling(d) Negative supercoilingThe question was posed to me during a job interview.I'd like to ask this question from DNA Supercoiling in division Genes and Chromosomes of Biochemistry |
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Answer» Correct answer is (B) Linking difference |
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| 9. |
When there is no net bending of the DNA axis upon itself, the DNA is said to be in a ____________(a) Elongated state(b) Compressed state(c) Relaxed state(d) Denatured stateThe question was asked during an interview.My query is from DNA Supercoiling in division Genes and Chromosomes of Biochemistry |
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Answer» The correct ANSWER is (c) RELAXED state |
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| 10. |
Cellular DNA is uncondensed throughout ____________(a) Prophase(b) Interphase(c) Telophase(d) AnaphaseI have been asked this question in unit test.The question is from The Structure Of Chromosomes in portion Genes and Chromosomes of Biochemistry |
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Answer» CORRECT OPTION is (b) Interphase For EXPLANATION: During interphase, the cell’s DNA is not condensed. |
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| 11. |
The sister chromatids separate at ____________(a) Prophase(b) Metaphase(c) Telophase(d) AnaphaseThis question was addressed to me in an interview.I need to ask this question from The Structure Of Chromosomes in section Genes and Chromosomes of Biochemistry |
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Answer» CORRECT answer is (d) ANAPHASE To explain I would say: During anaphase, each CHROMOSOMAL pair is separated into TWO identical and independent CHROMOSOMES. |
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| 12. |
Long interspersed elements are about ____________(a) 100 to 300 bp long(b) 200 to 400 bp long(c) 10 to 100 bp long(d) 6000 to 8000 bp longThis question was addressed to me in homework.My question is from Chromosomal Elements topic in chapter Genes and Chromosomes of Biochemistry |
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Answer» The correct CHOICE is (d) 6000 to 8000 BP LONG |
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| 13. |
Which of the following has beads on a string structure?(a) Chromosomes(b) Chromatin(c) Nucleosomes(d) HeterochromatinI had been asked this question in semester exam.My question is taken from The Structure Of Chromosomes in chapter Genes and Chromosomes of Biochemistry |
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Answer» Correct answer is (c) Nucleosomes |
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| 14. |
Which of the following is not a major class of chromatin proteins?(a) Histones(b) Topoisomerases(c) SMC proteins(d) CohesinsI got this question in an internship interview.Query is from The Structure Of Chromosomes topic in division Genes and Chromosomes of Biochemistry |
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Answer» The CORRECT ANSWER is (d) COHESINS |
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| 15. |
Short interspersed elements are about ____________(a) 100 to 300 bp long(b) 200 to 400 bp long(c) 10 to 100 bp long(d) 6000 to 8000 bp longI got this question in an interview for internship.The query is from Chromosomal Elements in section Genes and Chromosomes of Biochemistry |
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Answer» CORRECT answer is (a) 100 to 300 bp long The best explanation: SHORT INTERSPERSED elements (SINEs) are about 100 to 300 bp long. |
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| 16. |
The type I enzyme(s) is/are ____________(a) Topoisomerases I and III(b) Topoisomerases II(c) Topoisomerase IV(d) Topoisomerases I and IVThis question was addressed to me during an online exam.Query is from DNA Supercoiling topic in division Genes and Chromosomes of Biochemistry |
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Answer» Correct answer is (a) TOPOISOMERASES I and III |
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| 17. |
The DNA threads which appear inside the nucleus at the time of cell division?(a) Spindle fibers(b) Centrioles(c) Asters(d) ChromosomesThe question was asked in class test.My question is taken from The Structure Of Chromosomes in section Genes and Chromosomes of Biochemistry |
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Answer» Correct choice is (d) Chromosomes |
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| 18. |
The type of topoisomerases that can introduce negative supercoils is ____________(a) Type I(b) Type II(c) Type III(d) Type IVThis question was addressed to me by my college professor while I was bunking the class.The origin of the question is DNA Supercoiling in portion Genes and Chromosomes of Biochemistry |
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Answer» Correct ANSWER is (B) Type II |
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| 19. |
Which type of supercoiling takes the form of extended right-handed coils?(a) Plectonemic supercoiling(b) Solenoidal supercoiling(c) Negative supercoiling(d) Positive supercoilingThe question was posed to me in class test.I'm obligated to ask this question of DNA Supercoiling topic in portion Genes and Chromosomes of Biochemistry |
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Answer» Correct option is (a) Plectonemic SUPERCOILING |
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| 20. |
The enzyme responsible for the removal of supercoiling in replicating DNA ahead of the replication fork is ____________(a) Topoisomerase(b) Primase(c) DNA polymerase(d) HelicaseThe question was posed to me in examination.My query is from DNA Supercoiling in division Genes and Chromosomes of Biochemistry |
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Answer» CORRECT option is (a) Topoisomerase For EXPLANATION I would say: The enzymes that increase or decrease the EXTENT of DNA under-winding are TOPOISOMERASES. |
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| 21. |
The phenomenon of twisting around itself by a molecule to relieve helical stress is ____________(a) Supercoiling(b) Coiling(c) Elongation(d) CompressionI have been asked this question in examination.My question is based upon DNA Supercoiling topic in division Genes and Chromosomes of Biochemistry |
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Answer» The CORRECT OPTION is (a) SUPERCOILING |
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| 22. |
Which of the following histones bind to linker DNA?(a) H1(b) H2A(c) H2B(d) H3The question was posed to me in examination.Enquiry is from The Structure Of Chromosomes in division Genes and Chromosomes of Biochemistry |
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Answer» The correct choice is (a) H1 |
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| 23. |
Which of the following histones shows more sequence similarity among eukaryotic species?(a) H1(b) H2A(c) H2B(d) H3This question was posed to me during an internship interview.My question is from The Structure Of Chromosomes in chapter Genes and Chromosomes of Biochemistry |
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Answer» Right option is (d) H3 |
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| 24. |
Changing twist from the relaxed state requires adding energy and increases the ____________(a) Forces in molecule(b) Stress along molecule(c) Strain over molecule(d) None of the aboveThe question was asked during an online exam.My doubt is from DNA Supercoiling topic in section Genes and Chromosomes of Biochemistry |
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Answer» CORRECT answer is (b) Stress along MOLECULE Easiest explanation: Relaxed state is the condition at which there is no net DNA bending, changing TWIST from this state requires additional energy and increases the stress along the molecule. |
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| 25. |
The type of topoisomerases which generally relaxes DNA by removing negative supercoiling?(a) Type I(b) Type II(c) Type III(d) Type IVThis question was posed to me in final exam.I'm obligated to ask this question of DNA Supercoiling in chapter Genes and Chromosomes of Biochemistry |
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Answer» Right OPTION is (a) Type I |
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| 26. |
Which of the following is false about introns?(a) They are non-protein coding genes(b) They are protein coding genes(c) They are removed by splicing(d) Integral to gene expression regulationI got this question by my college professor while I was bunking the class.My doubt is from Chromosomal Elements in division Genes and Chromosomes of Biochemistry |
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Answer» Correct answer is (B) They are PROTEIN CODING GENES |
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| 27. |
Which of the following are essential to the condensation of chromosomes as cells enter mitosis?(a) Cohesins(b) Condensins(c) Histones(d) TopoisomerasesThe question was posed to me in an interview.Question is from The Structure Of Chromosomes in division Genes and Chromosomes of Biochemistry |
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Answer» CORRECT choice is (b) Condensins Explanation: Cohesins are IMPORTANT IMMEDIATELY after REPLICATION. |
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| 28. |
Which of the following plays a substantial role in linking together sister chromatids immediately after replication?(a) Cohesins(b) Condensins(c) Histones(d) TopoisomerasesThe question was asked during an interview.My question is based upon The Structure Of Chromosomes topic in chapter Genes and Chromosomes of Biochemistry |
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Answer» CORRECT answer is (a) Cohesins For explanation: The cohesins play a substantial role in linking TOGETHER sister chromatids IMMEDIATELY after replication and keeping them together as the chromosomes CONDENSE to metaphase. |
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| 29. |
Over-twisting of a molecule results in ____________(a) Negative supercoiling(b) Positive supercoiling(c) Elongation(d) CompressionI have been asked this question in semester exam.This is a very interesting question from DNA Supercoiling topic in section Genes and Chromosomes of Biochemistry |
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Answer» The CORRECT CHOICE is (b) Positive supercoiling |
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| 30. |
Which of the two organelles contain their own DNA and ribosomes?(a) Mitochondria and chloroplast(b) Endoplasmic reticulum and mitochondria(c) Golgi complex and mitochondria(d) Lysosomes and mitochondriaThis question was addressed to me in a national level competition.Enquiry is from Chromosomal Elements in division Genes and Chromosomes of Biochemistry |
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Answer» The correct answer is (a) MITOCHONDRIA and CHLOROPLAST |
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