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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 51. |
The genetic disorder which occurs due to defect in the synthesis o subunits of haemoglobin isA. AlkaptonuriaB. AlbinismC. ThalassemiaD. None of these |
| Answer» Correct Answer - C | |
| 52. |
Haemophilia, an X-linked recessive disease is caused due to deficiency ofA. Blood plasma and vitamin-KB. Blood platalets and haemoglobinC. Lack of clotting material and vitamin-KD. Allof the above |
| Answer» Correct Answer - C | |
| 53. |
It is well known that Queen Victoria of England was a carrier for haemophilia.Since this is a an X-linked disease,it can be predicted that:A. all of her sons would have had diseaseB. all her daugthers would have been carriersC. her father must definitely have had haemophiliaD. haemophilia would have occurred in more of her male than her female descendents |
| Answer» Correct Answer - D | |
| 54. |
Cri-du-chat syndrome in humans is caused by the :A. trisomy of 21st chromosomeB. loss of half of the long arm of chromosome 5C. loss of half of the short arm of choromosome 5D. fertilization of an XX egg by a normal Y- bearing sperm |
| Answer» Correct Answer - C | |
| 55. |
Cri-du-chat syndrome in is caused by the :A. deletionB. duplicationC. translocationD. paracentric inversion |
| Answer» Correct Answer - A | |
| 56. |
Which one is a hereditary disease?A. LeprosyB. CataractC. BlindnessD. Phenylketonuria |
| Answer» Correct Answer - D | |
| 57. |
The hereditary disease in which the urine of a person turns black on exposure to air due to the presence of homogentisic acid is known as:A. ketonuriaB. haematuriaC. phenylketonuriaD. alkaptonuria |
| Answer» Correct Answer - D | |
| 58. |
Blacking of urine when exposed to air a metabolic disorder in human beings. This is due toA. tyrosineB. phenylalanineC. Homogentisic acidD. valine replacing glutamine |
| Answer» Correct Answer - C | |
| 59. |
A man has a wound.Normally a bleeding would develops a clot and flow of blood stops.If this does not happen to the man then he probably suffers from :A. AIDSB. tetanusC. malarisD. haemophilia |
| Answer» Correct Answer - D | |
| 60. |
A cross between white-eyed female and red eyed male Drosophila gives red-eyed females and white-eyed females and red-eyed males.This is due to :A. mutation in maleB. mutation in femaleC. loss of sex chromosomeD. non disjunction of two X-chromosome in female |
| Answer» Correct Answer - D | |
| 61. |
The colour blindness is more likely to occur in males than in females becauseA. Genes for characters are located on the sex chromosomeB. The trait is dominant in males and recessive in femalesC. The Y-chromosomes of male have genes for distinguish coloursD. None of the above |
| Answer» Correct Answer - A | |
| 62. |
In humans chromosomal condition of male isA. 44 AA + XOB. 44 AA + XXYC. 44 AA + XXD. 44 AA + XY |
| Answer» Correct Answer - D | |
| 63. |
Colour blindness is found more in males than in females because :A. heterozygous females are colour blindB. males having affected Y-chromosome are colour blindC. males containing the single affected X-chromosome are colour blindD. affected X-chromosome has a much higer affinity to Y-chromosome as compared to unaffected X-chromosome |
| Answer» Correct Answer - C | |
| 64. |
Which of the following terms are related to barr body?A. Sex chromatinB. Murray barrC. Both (a) and (b)D. Criss-cross inheritance |
| Answer» Correct Answer - C | |
| 65. |
whichof the following represents the allosome complement of a super female?A. XYYB. XXXXC. XXYD. YYY |
| Answer» Correct Answer - B | |
| 66. |
Super males have chromosome numbersA. 43 + XY (45)B. 44 + XYY (47)C. 44 + XO (45)D. 44 + YO (45) |
| Answer» Correct Answer - B | |
| 67. |
Which of the following conditions in humans is correctly matched with its chromosomal abnormality/linkage Or An abnormal human male phenotype involving an extra X- chromosomes in a case ofA. Erythroblastosis foetalis -X linkedB. Klinefelter syndrome - 44 autosomes + XXYC. Down syndrome -44 autosomes +XOD. Colour blindness -Y linked |
| Answer» Correct Answer - B | |
| 68. |
Philadelphia chromosome ocurs in patients suffering fromA. RicketsB. HepatitisC. AlbinismD. Leukemia |
| Answer» Correct Answer - D | |
| 69. |
Which one of the following techniques is emloyed in human genetic counselling ?A. polyploidyB. amniocentesisC. pedigree anlaysisD. genetic engineering |
| Answer» Correct Answer - C | |
| 70. |
Which one of the following techniques is employed in human genetic counselling ?A. PolyploidyB. AmniocentesisC. Pedigree analysisD. Genetic engineering |
| Answer» Correct Answer - C | |
| 71. |
Erythroblastosis foetalis occurs:A. when the mother is Rh negative and the child is Rh positiveB. when the mother is Rh negative and the child is Rh negativeC. when the mother is negative and the child is positiveD. when the mother is Rh positive and the child is Rh negative |
| Answer» Correct Answer - A | |
| 72. |
Biologically marriage between which of the following is prohibited due to erythroblastosis foetalis ?A. `Rh^- ` boy and `Rh^+` girlB. `Rh^- ` boy and `Rh^-` girlC. `Rh^+ ` boy and `Rh^+` girlD. `Rh^+ ` boy and `Rh^-` girl |
| Answer» Correct Answer - D | |
| 73. |
Erythroblastosis foetalis occursA. When the mother is Rh negetive and the child is Rh positiveB. When the father and child are both negative, but the mother is positiveC. When the mother and child are both Rh positive, but the father is Rh negativeD. When the mother and father are Rh positive, but child is Rh negative |
| Answer» Correct Answer - A | |
| 74. |
The status of the foetus for genetic counselling can be determined by :A. foetocentesisB. amniocentesisC. amnioacidpathyD. all of these |
| Answer» Correct Answer - B | |
| 75. |
Which of the following would result in haemolysis of foetus ?A. Rh incompatibilityB. BO incompatibilityC. AB incompatibilityD. AO incompatibility |
| Answer» Correct Answer - A | |
| 76. |
In erythroblastosis foetails which factors of the mother pass trough placenta into the foetus ?A. Rh antigensB. AgglutininsC. Rh antibodiesD. AOB antibodies |
| Answer» Correct Answer - C | |
| 77. |
The second pregnancy of a woman terminates due to anaemia of the foetus. She has never had a blood transufion. On the basis of this, which of the following is correcA. child from the first pregnancy is Rh positiveB. The husband of woman is Rh positiveC. The woman is Rh negativeD. all the above |
| Answer» Correct Answer - D | |
| 78. |
In developing foetus ,erthoblastosis foetalis is caused by :A. haemolysisB. clumping of RBCsC. phagocytosis by WBCsD. failure of blood clotting |
| Answer» Correct Answer - A | |
| 79. |
Agglutinoges are not found in blood group:A. AB. OC. ABD. B |
| Answer» Correct Answer - B | |
| 80. |
Which of the following would result in haemolysis of foetus ?A. RH inoompatibilityB. BO incompatibilityC. AB incompatibilityD. AO incompstibility |
| Answer» Correct Answer - A | |
| 81. |
The chromosome pattern of turner syndrome usually have:A. 2A+XXYB. one XC. 2A + XXXD. Two X only |
| Answer» Correct Answer - B | |
| 82. |
Turner syndrome has ……….chromosome complement .A. XOB. XXYC. XXXD. XYY |
| Answer» Correct Answer - A | |
| 83. |
A person affected with phenylketonuria lacks an enzyme that converts the amino acid phenylalanine into :A. ValineB. ProlineC. HistidineD. Tyrosine |
| Answer» Correct Answer - D | |
| 84. |
Sickle-cell anaemia is caused due to the substitution of :A. Valine at the 6th position of alpha globin chain by glutamic acidB. Glutamic acid at the 6th position of beta globin chain by valineC. Valine at the 6th position of beta globin chain by glutamicD. Glycine at the 6th position of alpha globin chain by glutamic acid |
| Answer» Correct Answer - B | |
| 85. |
An example for sex influenced inheritance :A. HaemophiliaB. pattern baldnessC. Colour blindnessD. Down syndrome |
| Answer» Correct Answer - B | |
| 86. |
Baldness is :A. sex-linkedB. sex-controlledC. sex determinedD. non of these |
| Answer» Correct Answer - B | |
| 87. |
Baldness is more common in men than in women it could be explained on the basis thatA. It is due to male hormone and genes are not involvedB. Balndness genes are located on Y-chromosomeC. Genes of baldness are autosomal but influenced by androgensD. Genes of baldness are located on X-chromosome only |
| Answer» Correct Answer - C | |
| 88. |
Sex determination by chromosome diffrence in man and Drosophila is by mechanism called :A. XX-XOB. XX-XYC. ZZ-ZWD. (a) and (b) |
| Answer» Correct Answer - B | |
| 89. |
A child with IQ of 140 belongs to the category :A. geniusB. superiorC. averageD. most superior |
| Answer» Correct Answer - A | |
| 90. |
Male XX and female XY sometime occur due to :A. deletionB. detectionC. aneuploidyD. hormonal imbalance |
| Answer» Correct Answer - D | |
| 91. |
Between persons of which two blood group is the blood tranfused not possible :A. O and B (O donor )B. O and AB(AB donor )C. O and A(O donor )D. O and AB (AB recipient) |
| Answer» Correct Answer - B | |
| 92. |
A faily has five girls and no sons.Probability of son in the sixth child will be :A. `20%`B. `50%`C. `75%`D. `100%` |
|
Answer» Correct Answer - B Each delivery is an independent event,probability of male or female child will be 50-50%. |
|
| 93. |
A family has five girls and no sons. Probability of son in the sixth child will beA. 0.2B. 0.5C. 0.75D. 1 |
| Answer» Correct Answer - B | |
| 94. |
After the age of 40 , the percentage of syndrome increased in the offspring of a lady is due toA. Lady becomes weakB. Oocyte can show non-disjunctionC. Ovaries become weakD. Placenta becomes weak |
| Answer» Correct Answer - B | |
| 95. |
A person who is trisomic for chromosome 18th pair is :A. Down syndromeB. Edward syndromeC. Turner syndromeD. Cri-du-chat syndrome |
| Answer» Correct Answer - B | |
| 96. |
Down syndrome is caused by an extra copy of chromosome number 21. What percentage of offspring prodused by an affected mother and a normal father would be affected by this disorder?A. `50 %`B. `25 %`C. `100%`D. `75%` |
| Answer» Correct Answer - A | |
| 97. |
which one is true for klinefelter syndrome ?A. `{:(,"No of Barr bodies"," ","Expression ",),(,0,,XO,):}`B. `{:(,"No of Barr bodies"," ","Expression ",),(,1,,XO,):}`C. `{:(,"No of Barr bodies"," ","Expression ",),(,1,,XXY,):}`D. `{:(,"No of Barr bodies"," ","Expression ",),(,0,,XYY,):}` |
| Answer» Correct Answer - C | |
| 98. |
The sex chromosome constitution in a klinefelter male is :A. XOB. YOC. XXYD. XXX |
| Answer» Correct Answer - C | |
| 99. |
Assertion In human, female sex is determined by XX chromosome Reason Male sex is determined by XY-chromosome |
|
Answer» Correct Answer - B According to chromosome theory of sex-determination, male and female individuals would differ in their chromosome contitution. In female , two chromosomes are homomorphic (XX) and in males, these are heteromorphic (XY) |
|
| 100. |
The condition of sex chromosome in a male chid of Down syndrome will be :A. XOB. XXC. XYD. XXY |
| Answer» Correct Answer - C | |