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1.

The inner boundary membrane and inner cristal membrane are joined by ____(a) Mitochondrial junctions(b) Membrane junctions(c) Cristae junctions(d) Tubule junctionsThe question was asked in an online quiz.Question is from Mitochondrial Structure and Function in portion Mitochondrial Structure and Function of Cell Biology

Answer»

The correct choice is (c) Cristae junctions

To EXPLAIN I WOULD say: The inner boundary membrane and INTERNAL cristal membranes in the mitochondria are joined to one another by narrow tubular connections known as cristae junctions. The cristae are internal protrusions that hold the respiratory mechanism IMPORTANT for CELLULAR respiration.

2.

NADH and FADH2 is associated with respectively ____________(a) Complexes I and complex II(b) Complexes II and complex III(c) Complexes I and complex III(d) Complexes III and complex IVI have been asked this question during an internship interview.My enquiry is from Mitochondrial Structure and Function topic in section Mitochondrial Structure and Function of Cell Biology

Answer» RIGHT choice is (a) COMPLEXES I and complex II

To elaborate: When NADH is the ELECTRON donor, electrons enter the RESPIRATORY chain via complex I, which transfers electrons to Ubiquinone. FADH2 remains covalently attached to succinate dehydrogenase, a component of complex II. When FADH2 is donor, electron is directly passed to Ubiquinone.
3.

How many ATP molecules are produced per glucose molecules in eukaryotic Glycolysis?(a) 2 ATP(b) 3 ATP(c) 4 ATP(d) 6 ATPI have been asked this question in a job interview.I'm obligated to ask this question of Mitochondrial Structure and Function in division Mitochondrial Structure and Function of Cell Biology

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The correct CHOICE is (a) 2 ATP

The EXPLANATION is: The process of cellular respiration involves the following steps- Glycolysis, Kreb’s cycle and electron oxidation, which are involved in ENERGY production by utilizing carbohydrate. Energy is produced in the FORM of Adenosine triphosphate (ATP) molecules with 2 ATP molecules produced per GLUCOSE molecule in Glycolysis.

4.

Human mitochondrial DNA encodes for____________(a) 2 rRNAs(b) 3 rRNAs(c) 1 rRNA(d) 4 rRNAsI had been asked this question in class test.Question is taken from Mitochondrial Structure and Function topic in section Mitochondrial Structure and Function of Cell Biology

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The correct CHOICE is (a) 2 rRNAs

To elaborate: The mitochondria POSSESS their own GENETIC material and the machinery to MANUFACTURE their own RNAs and proteins. In humans, the mitochondrial DNA encodes for 2 ribosomal RNAs (rRNAs).

5.

Which part of mitochondria has almost 70-75% protein content?(a) Outer membrane(b) Inner membrane(c) Both outer and inner membrane(d) Intermembrane spaceThis question was posed to me in an interview for job.Question is from Mitochondrial Structure and Function topic in division Mitochondrial Structure and Function of Cell Biology

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The correct choice is (b) Inner membrane

Easy explanation: The outer membrane of MITOCHONDRIA is composed of approximately 50% lipid by weight and CONTAINS a mixture of different enzymes. The inner membrane contains more than 100 different polypeptides and has a very HIGH protein to lipid ratio. The protein CONTENT EXCEEDS 70% by weight.

6.

Mitochondria is the organ for ______(a) Cellular respiration(b) Cellular digestion(c) Cellular death(d) Cellular motilityI have been asked this question by my college professor while I was bunking the class.I need to ask this question from Mitochondrial Structure and Function topic in portion Mitochondrial Structure and Function of Cell Biology

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Right answer is (a) Cellular RESPIRATION

To explain: Mitochondria is a bean shaped organ in the cell cytoplasm. Its major role is cellular respiration. It utilizes OXYGEN and carbohydrate to release carbon dioxide and energy in the form of ATP. Cellular respiratory PROCESSES such as Kreb’s cycle and oxidative PHOSPHORYLATION takes place in mitochondria.

7.

The TCA cycle produces ____________(a) 2 NADH(b) 6 NADH(c) 8 NADH(d) 4 NADHThe question was asked by my college director while I was bunking the class.My doubt stems from Mitochondrial Structure and Function topic in division Mitochondrial Structure and Function of Cell Biology

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The correct option is (B) 6 NADH

The best I can explain: The primary PRODUCTS of the TCA cycle pathway are the REDUCED coenzymes, NADH and FADH2, which contain high energy ELECTRONS REMOVED from various substrates as they are oxidized. A total of 6 NADH are formed during one Krebs’ cycle process.

8.

How many ATP molecules are produced per Krebs’ Cycle in eukaryotes?(a) 2 ATP(b) 36 ATP(c) 38 ATP(d) 24 ATPThe question was asked in an online interview.Question is from Mitochondrial Structure and Function in section Mitochondrial Structure and Function of Cell Biology

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9.

Which of the following enzyme produced by peroxisomes are present in plant cell, but absent in human cell?(a) Catalase(b) Peroxidase(c) Uric acid oxidase(d) D – amino acid oxidaseThe question was asked in an international level competition.My question is from Mitochondrial Structure and Function topic in section Mitochondrial Structure and Function of Cell Biology

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Correct answer is (C) Uric acid oxidase

The best I can EXPLAIN: The peroxisomes in human cells lack Uric acid catalase which is present in plant cells. Due to this LACKING, the humans are EXPOSED to a DISEASE called gout.

10.

Who first discovered peroxisomes?(a) Christian de Duve(b) Boveri(c) J Rhodin(d) Van BenedenThis question was addressed to me in my homework.Question is from Mitochondrial Structure and Function in portion Mitochondrial Structure and Function of Cell Biology

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The correct answer is (a) Christian de Duve

To explain: Peroxisomes are small CELL organelles found in the cytoplasm of most EUKARYOTIC organisms. They we first described by J Rhodin in the year 1954. But peroxisomes were discovered to be a cell ORGANELLE by Christian de Duve in the year 1967.

11.

What enzyme is used to detoxify alcohol in our body?(a) Catalase(b) Peroxidase(c) Urea – catalase(d) AmylaseThe question was posed to me in an internship interview.This question is from Mitochondrial Structure and Function topic in section Mitochondrial Structure and Function of Cell Biology

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Correct answer is (B) Peroxidase

Explanation: Peroxidase is one of the ENZYMES produced by peroxisomes. They breakdown alcohol by transferring a hydrogen ATOMS to OXYGEN forming hydrogen peroxide which is later converted to water.

12.

Which cells in our body contains abundant peroxisomes?(a) Liver cells(b) Reproductive cells(c) Cardiac cells(d) Brain cellsI have been asked this question in examination.Question is from Mitochondrial Structure and Function topic in division Mitochondrial Structure and Function of Cell Biology

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The correct answer is (a) Liver cells

The explanation: The liver cells have a HIGH AMOUNT of peroxisomes so that they can DETOXIFY the chemicals in our body. The peroxisomes ALSO aid in the production of bile acids from CHOLESTEROL.

13.

In the electron transport chain, each pair of electron donated by FADH2 releases sufficient energy to produce __________(a) 3 ATPs(b) 1 ATP(c) 2 ATPs(d) 4 ATPsThis question was posed to me in unit test.Origin of the question is Mitochondrial Structure and Function topic in division Mitochondrial Structure and Function of Cell Biology

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The correct choice is (c) 2 ATPs

The EXPLANATION is: ELECTRON is donated by the REDUCED cofactor FADH2 to oxygen by electron transport chain. During the transfer, it releases SUFFICIENT ENERGY to drive the formation of approximately 2 ATP molecules.

14.

Glycolysis takes place in _____(a) Outer membrane of mitochondria(b) Inner membrane of mitochondria(c) Mitochondrial matrix(d) CytosolThis question was posed to me in an interview.My doubt stems from Mitochondrial Structure and Function in portion Mitochondrial Structure and Function of Cell Biology

Answer» RIGHT choice is (d) Cytosol

For explanation: The process of cellular respiration involves the following steps- Glycolysis, KREB’s cycle and electron oxidation. The Glycolysis STAGE occurs in cytoplasm and the Kreb’s cycle occurs in the MATRIX of mitochondria.
15.

Among which of the following Peroxisomes are absent?(a) Bacillus subtilis(b) Zea mays(c) Homo habilis(d) Euphlyctis hexadactylusI got this question in an interview for internship.Origin of the question is Mitochondrial Structure and Function topic in portion Mitochondrial Structure and Function of Cell Biology

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Correct answer is (a) BACILLUS subtilis

Explanation: Peroxisomes are only present in eukaryotic cells. Prokaryotic cells are devoid of peroxisomes THUS Bacillus subtilis is a BACTERIA and it LACKS peroxisomes.

16.

Which of the following is not involved in electron chain transport system?(a) Complexes I, II, II, IV(b) Ubiquinone(c) Cytochrome C(d) All of them are involvedI had been asked this question during an online exam.My question is based upon Mitochondrial Structure and Function in portion Mitochondrial Structure and Function of Cell Biology

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Right choice is (d) All of them are involved

To EXPLAIN I would say: Electron CARRIERS can be isolated as part of four distinct, asymmetric, membrane-spanning complexes known as complexes I, II, II and IV. Two of the electron transport CHAIN complexes, Ubiquinone and Cytochrome C are not part of any complexes. Ubiquinone is present as a pool of molecules dissolved in lipid bilayer and Cyt C is SOLUBLE PROTEIN in intermembrane space.

17.

Which part of mitochondria is responsible for the degradation of many enzymes?(a) Mitochondrial matrix(b) Cristae(c) Inner membrane(d) Outer membraneI had been asked this question in my homework.The query is from Mitochondrial Structure and Function in division Mitochondrial Structure and Function of Cell Biology

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Correct OPTION is (d) Outer membrane

The best explanation: The outer membrane of mitochondria is composed of approximately 50% lipid by weight and contains a MIXTURE of different enzymes. It is involved in diverse activities such as enzyme DEGRADATION. The oxidation of epinephrine, degradation of tryptophan and elongation of FATTY acid takes place in outer mitochondrial membrane.

18.

Which genetic disorder is associated with dysfunction of peroxisomes?(a) Parkinson’s disease(b) Down’s syndrome(c) Zellweger Syndrome(d) Bubble Boy SyndromeI had been asked this question in an online quiz.My doubt is from Mitochondrial Structure and Function topic in division Mitochondrial Structure and Function of Cell Biology

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Correct option is (C) Zellweger Syndrome

For explanation I would say: Zellweger is an autosomal recessive SYSTEMIC disorder caused by the impairment of PEROXISOMES biogenesis. They affect the brain, nerve, face and LIVER.

19.

What is the major role of peroxisomes in our body?(a) Breakdown of Formaldehyde(b) Breakdown of proteins(c) Breakdown of Hydrogen Peroxide(d) Breakdown of PhthalatesI got this question in an interview.This intriguing question comes from Mitochondrial Structure and Function in chapter Mitochondrial Structure and Function of Cell Biology

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The correct choice is (c) Breakdown of HYDROGEN Peroxide

The explanation is: The PEROXISOMES have an ENZYME CALLED catalase. This enzyme is used to breakdown Hydrogen Peroxide into water.

20.

Total number of ATPs formed by oxidation of one glucose molecule is ___________(a) 36 ATPs(b) 30 ATP(c) 32 ATPs(d) 34 ATPsI have been asked this question in unit test.My question is from Mitochondrial Structure and Function in section Mitochondrial Structure and Function of Cell Biology

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The correct choice is (a) 36 ATPs

To explain I would say: For oxidation of ONE GLUCOSE molecules, 2 ATP molecules are produced by glycolysis. 24 ATP molecules are produced by Kreb’s cycle and 10 ATP molecules is produced by electron oxidative chain. This adds up to 36 molecules ATP released by oxidation of one MOLECULE of glucose.

21.

The TCA cycle produces ___________(a) 2 GTPs(b) 1 GTP(c) 3 GTPs(d) 4 GTPsThe question was asked during an internship interview.My question comes from Mitochondrial Structure and Function topic in chapter Mitochondrial Structure and Function of Cell Biology

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The correct choice is (a) 2 GTPs

To explain I would say: The primary products of the TCA cycle PATHWAY are the reduced coenzymes, NADH and FADH2, which contain HIGH energy electrons removed from various substrates as they are oxidized. The Krebs’ cycle PRODUCES two GTP molecules during ONE cycle. 2 GTP molecules equivalents to 2 ATP molecules.

22.

In the inner membrane of mitochondria, there is one protein molecule for approximately every _______(a) 15 phospholipids(b) 25 phospholipids(c) 5 phospholipids(d) 10 phospholipidsThe question was asked in semester exam.Enquiry is from Mitochondrial Structure and Function topic in portion Mitochondrial Structure and Function of Cell Biology

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Correct choice is (a) 15 phospholipids

For explanation: The inner membrane contains more than 100 different polypeptides and has a very HIGH PROTEIN to lipid ratio. The protein content EXCEEDS 70% by weight. This corresponds to about one protein molecule for every 15 phospholipids.

23.

The protruding invaginated sheets inside mitochondria is known as _____(a) Cristae(b) Fimbrae(c) Hyphae(d) Cellular DigestionI had been asked this question by my school principal while I was bunking the class.I want to ask this question from Mitochondrial Structure and Function in chapter Mitochondrial Structure and Function of Cell Biology

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The correct choice is (a) Cristae

The EXPLANATION is: The structure of mitochondria under the microscope is bean SHAPED with inner and OUTER mitochondrial membranes surrounding it. The inner membrane invaginates INSIDE to produce finger-like protrusions KNOWN as the Cristae.

24.

The first stable compound of Kreb’s cycle is _____________(a) Citrate(b) Cis- Aconitate(c) Oxaloacetate(d) MalateI had been asked this question in an international level competition.My question is from Mitochondrial Structure and Function in division Mitochondrial Structure and Function of Cell Biology

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The correct CHOICE is (a) CITRATE

The best EXPLANATION: Kreb’s cycle has Citrate as its first stable compound. That is why it is also CALLED Citric Acid Cycle. Citrate is a compound containing three carboxylic acid groups and it is THUS also called Tricarboxylic Acid cycle or TCA cycle.

25.

The mitochondrial RNA polymerase is made up of _____________(a) 1 subunit(b) 2 subunits(c) 3 subunits(d) multiple subunitsI got this question during a job interview.My question is based upon Mitochondrial Structure and Function in section Mitochondrial Structure and Function of Cell Biology

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Right choice is (a) 1 subunit

The explanation is: Mitochondrial RNA polymerase helps in the synthesis of proteins from mitochondrial RNA. The mitochondrial RNA polymerase is unlike the multi-subunit RNA polymerase enzyme of prokaryotic and EUKARYOTIC cell and CONTAINS only a single subunit SIMILAR to CERTAIN bacterial VIRUSES.

26.

The mitochondrial DNA in humans encode for how many poplypeptides?(a) 15(b) 13(c) 12(d) 11I have been asked this question during an online interview.My doubt is from Mitochondrial Structure and Function topic in chapter Mitochondrial Structure and Function of Cell Biology

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Correct CHOICE is (b) 13

The best I can explain: The mitochondria possess their own genetic material and the machinery to manufacture their own RNAs and proteins. The mitochondrial DNA encodes a small number of POLYPEPTIDES which are 13 in humans. These are tightly integrated in the inner mitochondrial membrane along with polypeptides encoded by nuclear genes.

27.

Which organelle is used in the production of white matter in the nervous system?(a) Mitochondria(b) Peroxisomes(c) Endoplasmic Reticulum(d) RibosomesI had been asked this question in an online interview.Origin of the question is Mitochondrial Structure and Function in division Mitochondrial Structure and Function of Cell Biology

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Correct answer is (b) Peroxisomes

For EXPLANATION: Peroxisomes are found to be a VITAL CELL organelle for the PRODUCTION of white matter of the cell. The PROCESS is known as myelination.

28.

After glycolysis, which of the following is transported across the inner mitochondrial membrane into the matrix?(a) Pyruvate(b) Acetyl CoA(c) ATP molecules(d) Coenzyme AThe question was asked by my college professor while I was bunking the class.This question is from Mitochondrial Structure and Function in portion Mitochondrial Structure and Function of Cell Biology

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Right answer is (a) Pyruvate

Easy explanation: Each pyruvate molecule PRODUCED in cytosol during Glycolysis is transported across the INNER mitochondrial MEMBRANE into the mitochondrial matrix. Pyruvate is then decarboxylated to PRODUCE Acetyl group (CH3COO^–) The Acetyl group is transferred to Coenzyme A to produce acetyl CoA.

29.

Cardiolipin present in inner mitochondrial membrane plays a role in ___________(a) Formation of the respiratory mechanisms(b) Activation of proteins involved in Glycolysis(c) Activation of proteins involved in electron oxidation(d) Activation of proteinsThe question was asked during an interview for a job.My question is based upon Mitochondrial Structure and Function topic in chapter Mitochondrial Structure and Function of Cell Biology

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The CORRECT ANSWER is (c) Activation of proteins involved in electron oxidation

Best explanation: The inner membrane of MITOCHONDRIA is virtually DEVOID of cholesterol and rich in unusual phospholipid and cardiolipins, which is the characteristics of bacterial membrane, from which the inner MITOCHONDRIAL membrane has presumable evolved. Cardiolipin plays a role in facilitating the activity of several large protein complexes involved in lector transport and ATP synthesis.

30.

In the electron transport chain, each pair of electron transferred from NADH to oxygen releases sufficient energy to produce __________(a) 3 ATPs(b) 1 ATP(c) 2 ATPs(d) 4 ATPsThe question was posed to me in a national level competition.This question is from Mitochondrial Structure and Function topic in division Mitochondrial Structure and Function of Cell Biology

Answer» RIGHT ANSWER is (a) 3 ATPs

To elaborate: Electron is transported from the REDUCED COFACTOR NADH to oxygen by electron transport chain. During the transfer, it releases sufficient energy to drive the formation of approximately 3 ATP MOLECULES.
31.

What cell organelle assists in the oxidation of fatty acids along with peroxisomes?(a) Ribosome(b) Nucleus(c) Endoplasmic Reticulum(d) MitochondriaI had been asked this question in an interview for internship.This interesting question is from Mitochondrial Structure and Function in section Mitochondrial Structure and Function of Cell Biology

Answer» CORRECT choice is (d) MITOCHONDRIA

Easiest explanation: Peroxisomes and mitochondria helps in BREAKING long fatty acid chains to simpler SUBSTANCES by β-oxidation. This was FOUND by Lazarow and De Duve in 1976.
32.

What is the diameter of peroxisomes?(a) 0.2 – 0.5 µm(b) 0.1 – 1.0 µm(c) 1 – 5 µm(d) 1 – 10 µmI had been asked this question during an internship interview.My question is from Mitochondrial Structure and Function in section Mitochondrial Structure and Function of Cell Biology

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The correct CHOICE is (B) 0.1 – 1.0 µm

Explanation: PEROXISOMES are usually 0.1 – 1.0 µm in DIAMETER. They do not have a definite size, but they vary in the range with RESPECT to specific organisms.

33.

The TCA cycle produces _____________(a) 2 FADH2(b) 3 FADH2(c) 4 FADH2(d) 1 FADH2The question was posed to me during a job interview.I need to ask this question from Mitochondrial Structure and Function in division Mitochondrial Structure and Function of Cell Biology

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Correct choice is (a) 2 FADH2

To explain: The primary PRODUCTS of the TCA cycle pathway are the REDUCED coenzymes, NADH and FADH2, which contain HIGH energy electrons removed from various SUBSTRATES as they are oxidized. A total of 2 FADH2 are formed during one Krebs’ cycle process.

34.

Human mitochondrial DNA encodes for _________(a) 21 tRNAs(b) 31 tRNAs(c) 22 tRNA(d) 24 tRNAsI have been asked this question during an interview.This intriguing question comes from Mitochondrial Structure and Function in portion Mitochondrial Structure and Function of Cell Biology

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Right option is (c) 22 tRNA

The best I can explain: The mitochondria possess their own genetic MATERIAL and the machinery to manufacture their own RNAs and proteins. In humans, the mitochondrial DNA encodes for 2 ribosomal RNAs (rRNAs) and also 22 TRANSFER RNAs (tRNAs) that are USED in protein synthesis within the organelle.

35.

Porins are present in ____________(a) Inner membrane(b) Outer membrane(c) Both inner and outer membrane(d) Intermembrane spaceThe question was asked during an online exam.The above asked question is from Mitochondrial Structure and Function topic in portion Mitochondrial Structure and Function of Cell Biology

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