127 + Interview Questions in THE-GENETIC-MATERIAL IN GENERAL AWARENESS Page 1 InterviewSolution

1.	The eukaryotic genome differs from the prokaryotic genome because `:`A. repetitive sequence are present in eukaryotesB. the DNA is complexed with histones in prokaryotesC. genes in the former case are organised into operonsD. the DNA is circular and single stranded in prokaryotes
Answer» Correct Answer - A

Discussion

2.	Taylor demonstrated semiconservative chromosome replication in `:`A. Vicia fabaB. Ha La cellC. Pisum sativumD. Mouse liver cell
Answer» Correct Answer - A

Discussion

3.	DNA gyrase, the enzymes that participates in the process of DNA repliation is a type of `:`A. DNA ligaseB. DNA polymeraseC. DNA topoisomeraseD. Reverse transciptase
Answer» Correct Answer - C

Discussion

4.	Which of the following enzymes adds noncoding sequences at chromosome ends ?A. HelicaseB. TelomeraseC. DNA polymerase `beta`D. DNA polymerase `epsilon`
Answer» Correct Answer - B

Discussion

5.	Assertion (A) `:` DNA code is copied in the synthesis of m-RNA. Reason ( R ) `:` t-RNA moves out of nucleus and after attaching on ribosomes form the template.A. Both (A) and (R ) are true and (R ) is the correct explanation of (A )B. Both (A ) and (R ) are true but (R ) is not the correct explanation of (A)C. (A ) is true statement but (R ) is falseD. Both (A ) and (R ) are false
Answer» Correct Answer - C

Discussion

6.	Which of the following be named for DNA produced from RNA ?A. c-DNAB. Z-DNAC. A-DNAD. B-DNA
Answer» Correct Answer - A

Discussion

7.	The strand of DNA acting as template for m-RNA transcription is `:` A. Sense strand" "B. Coding strand C. Anti - sense " "D. Non-coding strand The correct answer is `:`A. A and CB. A and DC. B and CD. C and D
Answer» Correct Answer - D

Discussion

8.	A double strand DNA measures `34 mu` . How many nucleotide pairs will be present ?A. 10B. 104C. 100D. 105
Answer» Correct Answer - C

Discussion

9.	Which of the following pairs is not correctly matched ?A. ATP-The principial energy carrying compound in the cellB. Purine - Nitrogenous bases cytosine, thymine and uracilC. r-RNA- RNA molecules found in ribosomesD. Recombinant-DNA formed by joining of segment DNA of DNA from different sources
Answer» Correct Answer - B Cytosin, thymine and uracil are pyrimidines.

Discussion

10.	Nucleotide on hydrolysis does not give `:`A. purinesB. amino acidsC. pyrimidinesD. pentose sugar
Answer» Correct Answer - B Amino acid is a component of protein , not of nucleic acid.

Discussion

11.	Durning DNA replication, the strands separate byA. gyraseB. unwindaseC. topoisomeraseD. DNA polymerase
Answer» Correct Answer - B

Discussion

12.	DNA strands are antiparallel because of the presence of `:`A. H-bondsB. Prptide bondsC. Disulphide bondsD. Phosphodiester bonds
Answer» Correct Answer - D Phosphodiester bond connects `C_(3)`and `C_(5)` of adjacent deoxyribose sugars.

Discussion

13.	Adenosine is `:`A. purineB. pyrimidineC. nucleosideD. nucleotide
Answer» Correct Answer - C

Discussion

14.	A nucleoside is `:`A. sugar `+` phosphateB. purine`//` pyrimidine `+` sugarC. purine `//` pyrimidine`+` sugarD. purine`//` pyrimidine `+` phosphate
Answer» Correct Answer - B

Discussion

15.	There is no DNA inA. hair rootB. mature RBCsC. an enucleated ovumD. a mature spermatozoan
Answer» Correct Answer - B

Discussion

16.	A nucleoside differs from a nucleotide is not having `:`A. sugarB. phosphateC. nitrogen baseD. phosphate and sugar
Answer» Correct Answer - B A nucleoside consists of a purine or pyrimidine base linked to a pentose sugar. On the other hand, nucleotides are phosphate esters of nucleosides.

Discussion

17.	Which DNA replication startsA. the phosphodiester bonds between the adjacent nucleotides breakB. the bonds between the nitrogen base and deoxyribose sugar breakC. the leading strand produces Okazaki fragmentsD. the hydrogen bonds between the nucleotides of two strands break.
Answer» Correct Answer - D

Discussion

18.	The hereditary material (DNA) present in the bacterium E.coli is `:`A. single stranded straightB. single stranded circularC. double stranded straightD. double stranded circular
Answer» Correct Answer - D Hereditary material of all bacteria is double stranded DNA.

Discussion

19.	DNA replication is `:`A. continuous and conservativeB. semiconservative and discontiuousC. conservative and semidiscontinuousD. semiconservative and semidiscontinuous
Answer» Correct Answer - C

Discussion

20.	Mode of DNA replication in E. coli is `:`A. conservative and bidirectionalB. conservative and unidirectionalC. semiconservative and bidirectionalD. semiconservative and unidirectional
Answer» Correct Answer - C

Discussion

21.	The diameter of Z-DNA molecule is `:`A. `18Å`B. `22 Å`C. `45Å`D. `34Å`
Answer» Correct Answer - A

Discussion

22.	Z- DNA and B- DNA differ inA. number of helixB. base pairingC. conformationD. constitution of bases
Answer» Correct Answer - C

Discussion

23.	Melting of DNA at an elevated temperature` (70^(@)C)` is primarily due to the breakdown ofA. hydrogen bondsB. disulphide bondsC. glycosidic bondsD. phosphodiester bonds
Answer» Correct Answer - A

Discussion

24.	Z-DNA was discovered by `:`A. Wang and RichB. Watson and CrickC. Meselson and StahlD. Frankline and Wilkins
Answer» Correct Answer - A

Discussion

25.	Match the following `:` A. A=1,B=4,C=2,D=3B. A=2,B=3,C=1,D=4C. A=3,B=2,C=1,D=4D. A=2,B=3,C=4,D=1
Answer» Correct Answer - D

Discussion

26.	The chemical name of cytosine is `:`A. 6-amino purineB. 2-amino-6-oxopurineC. 4-amino-2-oxopyrimidineD. 5-methyl-2,4-dioxopyrimidine
Answer» Correct Answer - C

Discussion

27.	Match List I with List II and select the correct answer using the codes give below in the lists `:` A. A=1,B=4,C=3,D=2B. A=2,B=1,C=4,D=3C. A=3,B=2,C=1,D=4D. A=3,B=2,C=1,D=4
Answer» Correct Answer - C

Discussion

28.	The four nitrogen base sequence which form the code words for DNA language are `:`A. UTACB. ACTUC. ATCGD. AGCU
Answer» Correct Answer - C

Discussion

29.	Match the List I with List II and find out the correct answer from the code give below `:` A. A=1,B=2,C=4,D=3B. A=4,B=1,C=3,D=2C. A=3,B=2,C=1,D=4D. A=4,B=1,C=2,D=3
Answer» Correct Answer - D

Discussion

30.	Match List I with List II and select the correct answer using the code given below in the lists. A. 1,2 and 3 are correctB. 1 and 2 are correct but 3 is falseC. 1 is correct but 2 and 3 are falseD. 1 and 3 are correct but 2 is false
Answer» Correct Answer - D Restriction endonuclease cuts DNA at specific DNA sequence.

Discussion

31.	If the DNA of humans contains `3 xx 10^(9) bp`, and if an Okazaki fragment, on average, is 2000 bp long, how many initiation points of RNA primase are present in the genome ?A. `1.5xx10^(6)`B. `3.5 xx 10^(6)`C. `1.5xx10^(9)`D. `1.0 xx 10^(6)`
Answer» Correct Answer - A Divide the total number of base pairs by the size of the Okazaki fragment or `(3 xx 10^(9))//(2xx10^(3))=1.5xx10^(6))` initiation sites.

Discussion

32.	Okazaki segments are formed during or DNA multiplication is calledA. synthesized on the leading strand of DNA replication forkB. synthesized on the lagging strand of DNA by replication forkC. produced during the digestion of DNA by restriction endonucleaseD. produced by sonication of DNA sample
Answer» Correct Answer - B

Discussion

33.	Okazaki fragments are joined in a correct sequence by `:`A. PrimaseB. HelicaseC. DNA ligaseD. RNA polymerase
Answer» Correct Answer - C

Discussion

34.	Okazaki fragments are associated with which phenomenon ?A. TranslationB. TranscriptionC. Replication of DNAD. Reverse transcription
Answer» Correct Answer - C

Discussion

35.	The enzyme used to join the DNA fragments is :A. ligaseB. PrimaseC. EndonucleaseD. DNA polymerase
Answer» Correct Answer - A

Discussion

36.	The enzyme which relaxes supercoiled DNA is `:`A. PrimaseB. DNA gyraseC. Topoisomerase ID. DNA polymerase III
Answer» Correct Answer - C

Discussion

37.	Phosphodiester bond is present in `:`A. ADPB. ATPC. CAMPD. all of these
Answer» Correct Answer - D

Discussion

38.	During DNA replication, the addition of nucleotides on the lagging strand occursA. continuoulyB. discontinuouslyC. toward the replicating forkD. at a faster rate than leading strand
Answer» Correct Answer - B

Discussion

39.	During the replication of DNA, the synthesis of DNA on lagging strand takes place in segments, these segments are called `:`A. Satellite segmentsB. Okazaki segmentsC. Kornberg segmentsD. Double helix segments
Answer» Correct Answer - B

Discussion

40.	The double helical model of DNA resembles a twisted ladder in which the rungs of the ladder are `:`A. a paried G and C paried with TB. a purine paired with a pyrimidineC. sugar - phosphate paired with sugar-phosphateD. both(a) and (b) are correct
Answer» Correct Answer - B

Discussion

41.	What happed when heat killed S cells along with live R cells were injected into mice ?A. Mice died and showed live R cellsB. Mice died and showed live S cellsC. Mice died and showed dead R cellsD. Mice survived and showed live S cells
Answer» Correct Answer - B

Discussion

42.	DNA is not directly involved with the synthesis of the followingA. t-RNA moleculeB. protein moleculeC. m-RNA moleculeD. another DNA molecule
Answer» Correct Answer - B

Discussion

43.	Genes were first artificially synthesized by `:`A. GaltonB. WatsonC. MendelD. Khorana
Answer» Correct Answer - D

Discussion

44.	Replication is `:`A. DNA `rarr` DNAB. DNA` rarr` RNAC. RNA `rarr` DNAD. DNA` rarr` Proteins
Answer» Correct Answer - A

Discussion

45.	Duplication of DNA is termed `:`A. translationB. replicationC. transcriptionD. transduction
Answer» Correct Answer - B

Discussion

46.	DNA duplication takes place during `:`A. only in S phaseB. only in `G_(1)` phaseC. only in `G_(2)` phaseD. entire interphase
Answer» Correct Answer - A

Discussion

47.	DNA replicates semi-conservatively was first shown in `:`A. Vicia fabaB. E. coliC. DrosophilaD. Caenorhabditis elegans
Answer» Correct Answer - B

Discussion

48.	The two strands of DNA are held together by `:`A. peptide bondsB. S-SC. BONDSD. Hydrogen bonds
Answer» Correct Answer - C

Discussion

49.	DNA polymerase `lambda` promotes `:`A. DNA repaireB. Synthesis of leading strandC. Synthesis of lagging strandD. Replication of mitochondrial DNA
Answer» Correct Answer - D

Discussion

50.	DNA polymerase helps inA. renaturation of DNAB. proof reading of RNAC. joining monomers of DNAD. splitting of two DNA strands
Answer» Correct Answer - C

Discussion

Explore topic-wise InterviewSolutions in .

The eukaryotic genome differs from the prokaryotic genome because `:`A. repetitive sequence are present in eukaryotesB. the DNA is complexed with histones in prokaryotesC. genes in the former case are organised into operonsD. the DNA is circular and single stranded in prokaryotes

Taylor demonstrated semiconservative chromosome replication in `:`A. Vicia fabaB. Ha La cellC. Pisum sativumD. Mouse liver cell

DNA gyrase, the enzymes that participates in the process of DNA repliation is a type of `:`A. DNA ligaseB. DNA polymeraseC. DNA topoisomeraseD. Reverse transciptase

Which of the following enzymes adds noncoding sequences at chromosome ends ?A. HelicaseB. TelomeraseC. DNA polymerase `beta`D. DNA polymerase `epsilon`

Which of the following be named for DNA produced from RNA ?A. c-DNAB. Z-DNAC. A-DNAD. B-DNA

The strand of DNA acting as template for m-RNA transcription is `:` A. Sense strand" "B. Coding strand C. Anti - sense " "D. Non-coding strand The correct answer is `:`A. A and CB. A and DC. B and CD. C and D

A double strand DNA measures `34 mu` . How many nucleotide pairs will be present ?A. 10B. 104C. 100D. 105

Which of the following pairs is not correctly matched ?A. ATP-The principial energy carrying compound in the cellB. Purine - Nitrogenous bases cytosine, thymine and uracilC. r-RNA- RNA molecules found in ribosomesD. Recombinant-DNA formed by joining of segment DNA of DNA from different sources

Nucleotide on hydrolysis does not give `:`A. purinesB. amino acidsC. pyrimidinesD. pentose sugar

Durning DNA replication, the strands separate byA. gyraseB. unwindaseC. topoisomeraseD. DNA polymerase

DNA strands are antiparallel because of the presence of `:`A. H-bondsB. Prptide bondsC. Disulphide bondsD. Phosphodiester bonds

Adenosine is `:`A. purineB. pyrimidineC. nucleosideD. nucleotide

A nucleoside is `:`A. sugar `+` phosphateB. purine`//` pyrimidine `+` sugarC. purine `//` pyrimidine`+` sugarD. purine`//` pyrimidine `+` phosphate

There is no DNA inA. hair rootB. mature RBCsC. an enucleated ovumD. a mature spermatozoan

A nucleoside differs from a nucleotide is not having `:`A. sugarB. phosphateC. nitrogen baseD. phosphate and sugar

Which DNA replication startsA. the phosphodiester bonds between the adjacent nucleotides breakB. the bonds between the nitrogen base and deoxyribose sugar breakC. the leading strand produces Okazaki fragmentsD. the hydrogen bonds between the nucleotides of two strands break.

The hereditary material (DNA) present in the bacterium E.coli is `:`A. single stranded straightB. single stranded circularC. double stranded straightD. double stranded circular

DNA replication is `:`A. continuous and conservativeB. semiconservative and discontiuousC. conservative and semidiscontinuousD. semiconservative and semidiscontinuous

Mode of DNA replication in E. coli is `:`A. conservative and bidirectionalB. conservative and unidirectionalC. semiconservative and bidirectionalD. semiconservative and unidirectional

The diameter of Z-DNA molecule is `:`A. `18Å`B. `22 Å`C. `45Å`D. `34Å`

Z- DNA and B- DNA differ inA. number of helixB. base pairingC. conformationD. constitution of bases

Melting of DNA at an elevated temperature` (70^(@)C)` is primarily due to the breakdown ofA. hydrogen bondsB. disulphide bondsC. glycosidic bondsD. phosphodiester bonds

Z-DNA was discovered by `:`A. Wang and RichB. Watson and CrickC. Meselson and StahlD. Frankline and Wilkins

Match the following `:` A. A=1,B=4,C=2,D=3B. A=2,B=3,C=1,D=4C. A=3,B=2,C=1,D=4D. A=2,B=3,C=4,D=1

The chemical name of cytosine is `:`A. 6-amino purineB. 2-amino-6-oxopurineC. 4-amino-2-oxopyrimidineD. 5-methyl-2,4-dioxopyrimidine

Match List I with List II and select the correct answer using the codes give below in the lists `:` A. A=1,B=4,C=3,D=2B. A=2,B=1,C=4,D=3C. A=3,B=2,C=1,D=4D. A=3,B=2,C=1,D=4

The four nitrogen base sequence which form the code words for DNA language are `:`A. UTACB. ACTUC. ATCGD. AGCU

Match the List I with List II and find out the correct answer from the code give below `:` A. A=1,B=2,C=4,D=3B. A=4,B=1,C=3,D=2C. A=3,B=2,C=1,D=4D. A=4,B=1,C=2,D=3

Match List I with List II and select the correct answer using the code given below in the lists. A. 1,2 and 3 are correctB. 1 and 2 are correct but 3 is falseC. 1 is correct but 2 and 3 are falseD. 1 and 3 are correct but 2 is false

If the DNA of humans contains `3 xx 10^(9) bp`, and if an Okazaki fragment, on average, is 2000 bp long, how many initiation points of RNA primase are present in the genome ?A. `1.5xx10^(6)`B. `3.5 xx 10^(6)`C. `1.5xx10^(9)`D. `1.0 xx 10^(6)`

Okazaki segments are formed during or DNA multiplication is calledA. synthesized on the leading strand of DNA replication forkB. synthesized on the lagging strand of DNA by replication forkC. produced during the digestion of DNA by restriction endonucleaseD. produced by sonication of DNA sample

Okazaki fragments are joined in a correct sequence by `:`A. PrimaseB. HelicaseC. DNA ligaseD. RNA polymerase

Okazaki fragments are associated with which phenomenon ?A. TranslationB. TranscriptionC. Replication of DNAD. Reverse transcription

The enzyme used to join the DNA fragments is :A. ligaseB. PrimaseC. EndonucleaseD. DNA polymerase

The enzyme which relaxes supercoiled DNA is `:`A. PrimaseB. DNA gyraseC. Topoisomerase ID. DNA polymerase III

Phosphodiester bond is present in `:`A. ADPB. ATPC. CAMPD. all of these

During DNA replication, the addition of nucleotides on the lagging strand occursA. continuoulyB. discontinuouslyC. toward the replicating forkD. at a faster rate than leading strand

During the replication of DNA, the synthesis of DNA on lagging strand takes place in segments, these segments are called `:`A. Satellite segmentsB. Okazaki segmentsC. Kornberg segmentsD. Double helix segments

The double helical model of DNA resembles a twisted ladder in which the rungs of the ladder are `:`A. a paried G and C paried with TB. a purine paired with a pyrimidineC. sugar - phosphate paired with sugar-phosphateD. both(a) and (b) are correct

What happed when heat killed S cells along with live R cells were injected into mice ?A. Mice died and showed live R cellsB. Mice died and showed live S cellsC. Mice died and showed dead R cellsD. Mice survived and showed live S cells

DNA is not directly involved with the synthesis of the followingA. t-RNA moleculeB. protein moleculeC. m-RNA moleculeD. another DNA molecule

Genes were first artificially synthesized by `:`A. GaltonB. WatsonC. MendelD. Khorana

Replication is `:`A. DNA `rarr` DNAB. DNA` rarr` RNAC. RNA `rarr` DNAD. DNA` rarr` Proteins

Duplication of DNA is termed `:`A. translationB. replicationC. transcriptionD. transduction

DNA duplication takes place during `:`A. only in S phaseB. only in `G_(1)` phaseC. only in `G_(2)` phaseD. entire interphase

DNA replicates semi-conservatively was first shown in `:`A. Vicia fabaB. E. coliC. DrosophilaD. Caenorhabditis elegans

The two strands of DNA are held together by `:`A. peptide bondsB. S-SC. BONDSD. Hydrogen bonds

DNA polymerase `lambda` promotes `:`A. DNA repaireB. Synthesis of leading strandC. Synthesis of lagging strandD. Replication of mitochondrial DNA

DNA polymerase helps inA. renaturation of DNAB. proof reading of RNAC. joining monomers of DNAD. splitting of two DNA strands