InterviewSolution
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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 101. |
Who was awarded Noble prize for synthesis of RNA in 1959A. NirenbergB. S. OchoaC. A. KornbergD. H.G. Khorana |
| Answer» Correct Answer - B | |
| 102. |
mRNA direct the building of proteins through a sequience ofA. IntronsB. CodonsC. ExonsD. Anticodons |
| Answer» Correct Answer - B | |
| 103. |
Wobble hypothesis establishes `:`A. peptide chain formationB. initiation of peptide chainC. termination of peptide chainD. economy in t-RNA molecules |
| Answer» Correct Answer - D | |
| 104. |
The process of altering the code in the DNA sequence, the message reversed isA. deletionB. inversionC. translocationD. none of these |
| Answer» Correct Answer - B | |
| 105. |
Which of the following base sequences acts as a terminal codon during protein synthesis ?A. AUGB. GCGC. UAGD. AGA |
| Answer» Correct Answer - C | |
| 106. |
The termination signal for protein synthesis comes from `:`A. AUUB. UAAC. GUGD. CTT |
| Answer» Correct Answer - B | |
| 107. |
Which of the following codon is related to UAA and UAG functions ?A. UUUB. UGAC. AUGD. GUG |
| Answer» Correct Answer - B | |
| 108. |
Consider the following statements `:` Assertion (A) `:` Amber codon is a termination codon . Reason (R ) `:` If in a m-RNA, a termination codon is present, the protein synthesis stops abruptly whether the protein synthesis is complete or not. Now select you answer from code given below `:`A. Both (A ) and (R ) are true and the (R ) is the correct explanation of the (A)B. Both (A) and (R ) are true but the (R ) is not the correct explanation of the (A)C. (A) is true statement but (R ) is falseD. Both (A ) and (R ) are false |
| Answer» Correct Answer - B | |
| 109. |
Which one of the following codons for the same information as UGC ?A. UGUB. UGAC. UAGD. UGG |
| Answer» Correct Answer - A | |
| 110. |
Which of the following amino acids has only one codon ?A. ValineB. TyrosinC. IsoleucineD. Tryptophan |
| Answer» Correct Answer - D | |
| 111. |
Which one of the following is catalysed by the presence of enzyme peptidyl transferase ?A. Peptide bond formationB. Transfer of a amino acidC. Transfer of peptide bondsD. Transfer ofribosomes units |
| Answer» Correct Answer - A | |
| 112. |
In which direction does a polypeptide chain being translated from m-RNA on a ribosome grow ?A. From N terminus to C terminusB. From C terminus to N terminusC. It depends on the RNA being synthesizedD. It depends on the protein being synthesized |
| Answer» Correct Answer - A | |
| 113. |
Translation of genetic information results in the synthesis of `:`A. DNAB. hn-RNAC. m-RNAD. polypeptide chain |
| Answer» Correct Answer - D | |
| 114. |
Length of m-RNA that carries information for complete polypeptide synthesis is `:`A. mutonB. codonC. operonD. cistron |
| Answer» Correct Answer - D | |
| 115. |
Synthesis of polypeptide over m-RNA is `:`A. translationB. transductionC. transformationD. transcription |
| Answer» Correct Answer - A | |
| 116. |
Codes of m-RNA and proteins are `:`A. colinearB. irregularC. coplanarD. nonlinear |
| Answer» Correct Answer - A | |
| 117. |
After a mutation at a genetic locus the character of an organism chagnes due to the change inA. Protein structureB. DNA replicationC. Protein synthesis patternD. RNA transcription pattern |
| Answer» Correct Answer - D | |
| 118. |
During transcription, if the nucleotide sequence of the DNA strand that is being coded is ATACG, then the nucleotide sequence in the m RNA would beA. UATGCB. TATGCC. UAUGCD. TCTGG |
| Answer» Correct Answer - C | |
| 119. |
A potein inhibitor of protein synthesis that acts as an analogue of aminacyl-t-RNA is `:`A. rifampicinB. promycinC. mitomyociin CD. streptomycin |
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Answer» Correct Answer - B Puromycin is a structural analogue of the aminoacyl end of the t-RNA . It irreversibly reacts with the peptidyl t-RNA, thereby terminating protein synthesis. |
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| 120. |
Which one of the following also acts as a catalyst in a becterial cell Or Which one of the following rRNA acts as stuctural RNA as well as ribozyme in bacterialA. sn-RNAB. hn-RNAC. 5 sr-RNAD. 23 sr-RNA |
| Answer» Correct Answer - D | |
| 121. |
The most stable RNA in the cell is `:`A. r-RNAB. s-RNAC. r-RNAD. m-RNA |
| Answer» Correct Answer - A | |
| 122. |
The binding site of t-RNA with m-RNA and amino acids respectively are `:`A. m-RNA with DHU loop and amino acid with CCA endB. m-RNA with CCA end and amino acid with anticodon loopC. m-RNA with anticodon loop and amino with DHU loopD. m-RNA with anticodon loop and amino acid with CCA end |
| Answer» Correct Answer - D | |
| 123. |
Most abundant RNA in a cell is `:`A. t-RNAB. r-RNAC. m-RNAD. primary RNA |
| Answer» Correct Answer - B | |
| 124. |
An anticodon of t-RNA can recognize more than one codon of m-RNA . It is `:`A. Wobble hypothesisB. Template hypothesisC. Gene flow hypothesisD. Richmond and Lang effect |
| Answer» Correct Answer - A | |
| 125. |
Codon of m-RNA and anticodon of t-RNA is made of `:`A. a set off two nitrogen basesB. a set of three out of U,A,C and GC. a set of three and two respectivelyD. three and one nitrogen bases respectively |
| Answer» Correct Answer - B | |
| 126. |
Anticodon loop of t-RNA contain `:`A. 3 paired basesB. 7 unpaired basesC. 5 paired basesD. 5 unpaired bases |
| Answer» Correct Answer - B | |
| 127. |
Choose the anticodon present on t-RNA that carries the amino acid methionine `:`A. UACB. AUGC. GCUD. UGC |
| Answer» Correct Answer - A | |
| 128. |
Clover leaf secondary structure of t-RNA has anticodon arm, which`:`A. contains in its loop three nucleotides of the anticodonB. contains in its loop three nucleotides of the codonC. contains in tis no nucleotidesD. both (a) and (b) correct |
| Answer» Correct Answer - A | |
| 129. |
A ribose nucleotide is `:`A. Uracil-Pentose sugar-phosphateB. Guanine-pentose sugar-phosphateC. Thymine - pentose sugar-phosphateD. Cytosine-pentose sugar-phosphate |
| Answer» Correct Answer - A | |
| 130. |
Uridine monophosphate is found in `:`A. DNAB. RNAC. Cell wallD. Lysosome |
| Answer» Correct Answer - B | |
| 131. |
Adenine `+` Ribose `+` Phosphate form `:`A. adenosineB. adenylic acidC. adenosine diphosphateD. adenosine triphosphate |
| Answer» Correct Answer - B | |
| 132. |
Activation of an amino acid during protein synthesis requires a participiation of specific molecule of `:`A. m-RNAB. t-RNAC. r-RNAD. none of the above |
| Answer» Correct Answer - D | |
| 133. |
Adenine of transfer RNA will pair with `:`A. uracilB. cytosine and uracilC. thymineD. guanine |
|
Answer» Correct Answer - A Thymine is absent in RNA. |
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| 134. |
In RNA, the thymine is replaced by `:`A. guanineB. adenineC. uracilD. cytosine |
| Answer» Correct Answer - C | |
| 135. |
Thymine is present in which of the following ?A. t-RNAB. ribosomal RNAC. mammalian m-RNAD. prokaryotic m-RNA |
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Answer» Correct Answer - A The uracil replaces thymine in RNA with one minor exception. All t-RNA contain one thymine linked to a ribose sugar. |
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| 136. |
How many high energy phosphate bond equivalents are utilized in the process of activation of amino acids for protein synthesis ?A. oneB. twoC. zeroD. three |
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Answer» Correct Answer - B ATP is required for the esterification of amino acids to their corresponding t-RNAs. Since ATP is hydrolyzed to AMP and Ppi during the reaction,the equivalent of two -high energy phosphate bonds is utilized. |
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| 137. |
All the following descriptions of eukaryotic RNA are true except `:`A. RNA is normaly single strandedB. The ratio of ribose to base equals oneC. Units of uridine equals units of adenineD. It derives from antiparallel, complementary DNA |
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Answer» Correct Answer - C RNA is synthesized from DNA as single stranded, linear molecules. Since it is not doulbe stranded, the concentration of different bases in RNA is variable. |
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| 138. |
The type of RNA specifically responsible for directing the proper sequence of amino acids in protein synthesis is `:`A. r-RNA sequenceB. t-RNAC. m-RNAD. chromosomal RNA |
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Answer» Correct Answer - C Because m-RNA carries the triplet codons responsible for sequence of amino acids in protein. |
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| 139. |
Which of the following pairs is correctly matched ?A. Ribosomal RNA - Carries amino acids to the site of protein synthesisB. Transcription - Process by which protein is synthesizedC. Translation - Process by which m-RNA carries the information from nucleus to the ribosomeD. Anticodon - Site of t-RNA molecule that contains complementary bases to the triplet code on the m-RNA |
| Answer» Correct Answer - D | |
| 140. |
Which of the following is not a nonsense (stop ) codon ?A. UAAB. UAGC. UGAD. UGG |
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Answer» Correct Answer - D UGG codes for the amino acid tryptophan. |
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| 141. |
Dr. Hargovind Khorana deuced the code for which of the following amino acidsA. Serine and leucineB. Isoleucine and leucineC. Valine and glutamine acidD. Phenylalanine and methionine |
| Answer» Correct Answer - A | |
| 142. |
During protein synthesis in an organism at one point the process comes to a halt. Select the group of the three codons from the following, from which anyone of the three could bring about this halt `:`A. UUU,UCC,UAUB. UUC,UUA,UACC. UAG,UGA,UAAD. UUG,UCA,UCG |
| Answer» Correct Answer - C | |
| 143. |
The genes are responsible for growthe and differentiation in an organism through regulation on `:`A. translocationB. transformationC. transduction and translationD. transcription and translation |
| Answer» Correct Answer - D | |
| 144. |
The genetic code `:`A. is ambiguousB. is degenerateC. is different for prokaryotes and eukaryotesD. has changed during the course of recent evolution |
| Answer» Correct Answer - B | |
| 145. |
A degneracy of genetci code was found by `:`A. OchoaB. KhoranaC. McClintockD. Bernfield and Nirenberg |
| Answer» Correct Answer - D | |