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Aldehyde with atleast one alpha hydrogen undergo aldol condensation. Two molecles of same or different aldehydes take part in such condensation. Ketones under similar condition give ketol condensatio. These reactions is best done with Ba(OH_(2)) . intramolecular aldol condensation is given by dialhydes, diketones aldol condensation is given by dialdehydes, diketones or keto aldehydes. The diketones should be 2,3, 2,6, 2,7 and 2,8 diketones. Intramolecular aldol condensation is the best method for prepartion of five and six memebered ring. For example: CH_(3)-overset(O)overset(||)C-H+CH_(3)-overset(O)overset(||)C-overset(NaOH(dil.))rarrCH_(3)-underset(H)underset(|)overset(OH)overset(|)C-CH_(2)CHO Cyclohexanone when treated withBa(OH)_(2) gives, as a result of aldol condensation. |
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