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Compound whichrotates theplanepolarisedlightisknown asopticallyactivecompound. On thebasisofdirectionof rotationtwoformsof an opticallyactivecompoundsare termedas dextro andlaevo rotatory. The twoare termedas enantiomers. Ifwe have a1 : 1mixtureof d andl isomersof a given chiralcompound, opticalrotation of suchmixtureis zeroSucha mixtureis optically inactive and is calleda recemic modification. Thenetspecificrotation of any mixtureof the dand isomersof a givenchiral compoundis equalto the weightedaverageof the rotations due to boththe isomersMathematicallyif can beexpressedas : [alpha]_(net) =f_(d) [alpha_(d)] + f_(1) [alpha_(l)] Where f_(a) and f_(l)are fractionsof d and l isomersrespectively and [alpha_(d)] , [alpha_(l)] are theirspecificrotationsWhat is theenantiomericexcess in anypuresampleof anopticallyactivesubstance ? |
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