1.

Define the followingterms in relation to proteins : (i) Peptide linkage . (ii) Denaturation.

Answer»

Solution :(i) PEPTIDE linkage: Proteins are polymers of aminoacidsconnected to each other by peptide linkage,Chemically peptide linkageis an amideformed between - COOH group and `- NH_(2)`group. Forexample, whencarboxyl group of GLYCRINE combines alanine , we getglycylalanine .
`H_(2)N - underset("Glycine")(CH_(2)) - COOH + H_(2)N - underset("Alanine")underset(CH_(3))underset(|)(CH) - COOH`

(ii) Denaturation: Whena protein innativeform is subjectedto physical changelikechangesdistrubed . DUETO thisglobulesunfold and HELIX get uncoiled and theprotein loses itsbioloigicalactivity . Thisis calleddenaturationof protein.
Duringdenaturation , thesecondary and tertiary structuresaredestroyed butprimarystructure remains intact . Coagulationof egg on boilingand curdling of milk are examples of denaturation .


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