Define the term therapeutic index. – InterviewSolution

1.	Define the term therapeutic index.
Answer» Solution :(i) Therapeutic index is DEFINED as the ratio between the maximum tolerated dose of a drug (above which it becomes toxic) and the minimum curative dose (below which the drug is INEFFECTIVE) (II) HIGHER the value of therapeutic index, safer is the drug.

Discussion

No Comment Found

Related InterviewSolutions

Which of the following compounds is not cleaved by HI even at 525 K ?
To a 25 mL H_(2)O_(2) solution excess of an acidified solution of potassium iodide was added. The iodine liberated required 20 " mL of " 0.3 N sodium thiosulphate solution Calculate the volume strength of H_(2)O_(2) solution.
The suggested mechanism of a reaction is : (a) A+BhArrD("fast) "(b)A+Drarr2C("slow")Write the balanced equation of the reaction if its experimentally deduced rate equation is , rate k=[A]^(2)[B] Find the intermediate formed during the course of the reaction . Does the predicted rate law from the mechanism match the experimental rate law ?
Which of these changes with time for a first-order reaction A Rate of reaction B . Rate constant C . Half-life
What is the hybridisation of central atom in the product obtained along with hydrofluoric acid when complete hydrolysis of Xenon Hexa Fluoride takes place ?
Which of the following amino acid forms sulphide bond in polypeptide
Which of following pair is Diastereomers:
What is the major product of the following reaction CH_3C-=C-CH_2-CH_3overset("1 mole of " Cl_2)to
Which polymer is used in petrol tank linings ?
Which of the following carbohydrates are branched polymer of glucose ?