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Epidemic dropsy is due to:1. Ergot2. BOAA3. Aflatoxin4. Sanguinarine

Answer» Correct Answer - Option 4 : Sanguinarine

Concept:

  • Sanguinarine is a major alkaloid of Argemone oil.
  • Epidemic dropsy occurs when edible oils are adultered by Argemone oil.
  • Sanguinarine acts on capillaries. There is capillary dilatation, proliferation, and increased capillary permeability. It leads to edema and hypovolemia.

  • Epidemic dropsy is characterized by gastroenteric symptoms followed by cutaneous erythema and pigmentation. Respiratory and cardiac symptoms may also be present.

Explanation:

  • Ergot is a fungus that grows on wheat. The reaction associated with ergot is St. Anthony's fire.
  • BOAA that is beta-N-oxalylamino-L-alanine is associated with lathyrism.
  • Aflatoxins can be responsible for the poisoning in humans. The toxins are produced by fungi found on crops such as maize, cottonseed, and tree nuts.


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