Saved Bookmarks
| 1. |
Explain Levine and hauser acetylation. |
|
Answer» Solution :The nitriles containing `ALPHA`- hydrogen also undergo condensation with esters in the presence of sodamine in ETHER to form ketonitriles. This reaction is known as Levine and hauser acetylation. `CH_(3)-underset("Ethyl PROPIONATE")(CH_(2))-overset(O)overset(||)(C)-OC_(2)H_(5)+underset("Ethane nitrile")(CH_(3)CN)underset((ii) H^(+))overset((i)NaNH_(2)-NH_(3))(to)underset(3-"Ketopentane nitrile")(CH_(3)-CH_(2)-overset(O)overset(||)(C)-CH_(2)CN)+underset("Ethanol")(C_(2)H_(5)OH)` |
|