1.

Glycin has the structural formula NH_(2)-CH_(2)-COOH. Glycine has two dissociation constant for which K_(a)" and " K_(b) are 1.6xx10^(-10)" and "K_(b) is 2.5xx10^(12). Calculate the isoelectric point of glycine [Hint : If your answer is 5.12 then fill 0512 in OMR sheet. If your answer is 8.02 then fill 0802 in OMR sheet]

Answer»


Solution :`pI=overset(pK_(A1)+pK_(a2))underset(2)_""pK_(a)=-logK_(a)`
`=(9.7958+2.39)/2=6.09`
`pK_(a1)=-logK_(a)""pK_(B1)=-logK_(b)`
`pK_(a1)=-log1.6xx10^(-10)""pK_(b1)=-log2.5xx10^(-12)`
`pK_(a1)=9.79""pK_(b1)=11.6`
`pK_(a1)+pK_(b1)=14`
`pK_(a2)+11.6=14`
`pK_(a2)=2.3979`


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