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How are OLV liposomes made?(a) 2-10 bilayers of lipid(b) Series of concentric bilayers of lipid(c) A single bilayer of lipid(d) 100 bilayer of lipidThis question was addressed to me in class test.Query is from Biopharmaceuticals in section Biopharmaceuticals of Drug Biotechnology

Answer» CORRECT choice is (a) 2-10 bilayers of LIPID

The explanation: OLV is also known as oligolamellar VESICLES. These are made up of 2-10 bilayers of lipid surrounding a large internal volume which will be consisting of the drug. MLV is made up of a series of CONCENTRIC bilayers of lipids. ULV is made of a single layer of lipids. There can be varying sizes from 20-40 nm to 1000 nm.


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