1.

How do enzyme inhibitors work ? Distinguish between competitive and non- competitive enzyme inhibitors.

Answer»

Solution :An enzyme INHIBITOR either BLOCKS the active site of enzyme or changes the shape of the active site by binding at an allosteric site. They are of TWO types :
(i) Competitive enzyme inhibitor competes with natural substance for theirattachment on the active sites of enzymes.
(ii) Non-competitive enzyme inhibitor binds at allosteric site and changes THESHAPE of the active site in such a way that the SUBSTRATE cannot recognize it.


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