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How is penicillin stored?(a) Filtration(b) Crystallization(c) Distillation(d) SublimationThis question was posed to me in exam.This question is from Production of Antibiotics (Isolation of Fermentation Products) topic in division Antibiotics & Enzyme Immobilization of Drug Biotechnology

Answer»

The correct choice is (b) Crystallization

For explanation: Pure metal salts of penicillin can be SAFELY sterilized by dry heat if DESIRED. Thereafter, the aqueous solution of penicillin is subjected to crystallization. The alkali metal salts of penicillin are extremely soluble in WATER, and methods THEREFORE known for crystallizing them have employed organic solvents under nearly anhydrous CONDITIONS.



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