Imine formation using an aldehyde/ketone and primary amine is acid - c – InterviewSolution

1.	Imine formation using an aldehyde/ketone and primary amine is acid - catalyzed, yet the rate drops below pH 4.5. Why does the rate drop below this pH?
Answer» The CARBINOLAMINE intermediate is stable at LOW pH The IMINE product is hydrolyzed at low pH Protonation of the amine DECREASES its nucleophilicity The amine is hydrolyzed at low pH Answer :C

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