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Inhibin is secreted by:1. Corpus luteum2. Stroma3. Leydig cells4. Surface epithelium

Answer» Correct Answer - Option 1 : Corpus luteum

Explanation

  • Inhibin is a gonadal hormone that has a negative role in the secretion of FSH from the pituitary.
  • The activin and Inhibin hypothesis was formulated in the late 1970s.

 Secretion

  • In females, it is secreted by the Corpus luteum, placenta, gonads and pituitary. 
  • In males, it is secreted by Sertoli cells in the testes. 

Action

  • Inhibits FSH production. The exact mechanism is unknown.
  • Regulates spermatogenesis.

  •  Elevated inhibin A suggests a fetus with down syndrome. 
  • Inhibin A is a marker in the diagnosis of ovarian cancer.
  • Positive test for Inhibin B in males suggestive of azoospermia.


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