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Osmotic pressure controlled systems work on the principle of osmotic pressure releasing the drug at constant 1st order kinetics.(a) True(b) FalseI got this question in an interview.My question is taken from Biopharmaceuticals topic in chapter Biopharmaceuticals of Drug Biotechnology

Answer»

Right option is (B) False

Best explanation: Osmotic pressure controlled systems are formulated such that they RELEASE the drug constantly at a zero order rate. The CORE comprises of the drug and an osmotically active substance such as POTASSIUM chloride or mannitol which will be SURROUNDED by a rigid semipermeable membrane coating such as ester or cellulose ester.



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