Need help. This scanner and its software worked fine like a month ago. I've UNINSTALLED and reinstalled uncountable times, turn it on, turn it off, reboot the computer, you name it. Specifically I'm having problems with the HP Solution center. I think a lot of HP stuff has gotten left in the registry and is a huge part of why the uninstall and reinstall is not working. I'm afraid to edit the registry because my computer is a Compaq Presario so I need to be sure what ever I delete from the registry is for the HP Photosmart C5180 only. Can you help? I'm running Windows Vista.In regards to this " you name it" have you (after uninstalling all the software for the printer) disconnected all cables from the printer (usb/power) from the printer to the computer? Then using the manual followed the precise sequence for installing the printer as if it were new.truenorth
P.S. I do NOT recommend you do anything to the registry.yes, I have also tried unplugging both the power and usb cords. I ran HP scan diagnostic utility and it confirms there are issues with the registry.Are you still eligible for FREE tech support on this printer? I really don't recommend nor will most members of the forums suggest you do things in your computer registry (unless you feel comfortable from KNOWLEDGE and experience to do so). I am a bit surprised that if all software has been REMOVED that a new install does not correct the registry issues.
I purused the HP site looking for solutions for this fault and found this. HOPE it helps.
http://h30434.www3.hp.com/t5/Printer-All-in-One-Software-and/Fix-for-recent-HP-solution-center-cannot-message/td-p/220133
truenorthAfter the next time you uninstall the software try running revo unstaller.

http://www.revouninstaller.com/revo_uninstaller_free_download.html

Some software leave remnants after a standard uninstall and if that's your problem it may help.  It was designed to repair sloppy uninstalls.

By all means, do NOT make changes in the registry unless you are 100% sure of what you are doing.  It's OK to look around, just be careful about what you do.That Revo software is where its at! HP's uninstall must really suck because Revo took over 6,000 related ITEMS out. I held my breath when I rebooted but my computer is still here. I'm doing a new install now of the printer software. Fingers crossed.