Recently my mouse has been "unresponding" when I am playing a game or just browsing the internet or anything for that matter the mouse will randomly stop moving and I can't left click or right click or anything ALMOST as if it's being undetected by my system, but recently I have looked at my mouse when it goes through these spells and the laser in the mouse that detects MOVEMENT is still on and the mouse acceleration light is still on so I don't know why the mouse itself doesn't work and this hasn't started happen until recently but I have noticed that it is happening more often and the time that the mouse is out is lasting longer and longer. Also I have tried replugging my mouse into a different usb I originally had my mouse in a 2.0 then I switched it to a different 2.0 and it still had the same effect then I switched it to a 3.0 and it still has this problem.  Mouse problems can be in software. Yet more often it is case of the wires have become damaged.    You might not see the damage. The quick way to test is to try another mouse.
BTW: Cost of a new mouse might not be a INDICATION of quality. Price often varies for other reasons. A standard optical mouse is about $10 from a on-line store. ALWAYS good to have a spare on hand, especially when you play games a lot.