unplugged power supply to VACCUUM out tower - now the secondary drive 1 is not found when I power back up. is that the disk drive and is there anyway to go around it? in the BIOS maybe?
Re-check all the ribbon cables to the drives...you didn't state how many and what type of drives you have so this is guesswork.

On a side note you should NEVER use a vacuum inside a computer case...they generate huge amounts of static electricity and you risk frying expensive components...

Post back with more details.Thanks for the FYI on the vacuuming - even if it's too late this time.
I have the C drive, a disk drive (A) and two CD drives (D&E). I only unplugged the ribbong cables to the C & A drives, and have tried unplugging & replugging them in - no LUCK. The power supply was chugging in the first place & I've had tons of remodeling going on so that's why I vacuumed in the 1st place.
I tried changing the boot order to start w/ C in case it was just the A drive - again no luck. now it can't find the primary or secondary drives. Guess I need to call the geek squad.
Buy a new IDE ribbon cable...
For now disconnect the CDRoms til we get the hard drive detected.
On bootup hit Delete, F2, or whatever command gets you into setup.
In the second or third screen in setup there will be an autodetect option for your drives...run it and see if this recognises your HDD. If so hit F10 to save changes and Exit.
The machine will automatically re-boot and you should have your drive back now...