I have recently bought a new computer (tower).
I Installed Windows XP with service pack 3, I Initially had problems with my wireless keyboard and mouse. Once I had changed the Bios and fixed problems with the USB ports I found they worked.
This lasted for 3 weeks, and then I booted up one morning & found they would not work.
My mouse and keyboard I have had for 3 years plus. (Worked well on previous computer with recently installed new version of XP as above)
My new mother board is a Gigabyte S-Series GA-MA69VM-S2
With a AMD Athlon X2 CPU
Microsoft Wireless OPTICAL Mouse 2.0A
Microsoft Wireless Comfort Keyboard 1.0A
I tried as system restore to a date when they worked X.
I looked in device manager, no problems, all working well X.
Re checked the Bios all ok, USB key board enabled X
Reinstalled drivers for Intelipoint Mouse and Key board X.
Checked my mouse, keyboard, and receiver are working well on my laptop. Yes the laptop detected them and installed drivers within 2 min, they all worked well.
I tried using different USB ports front and back.X
When I unplug and replug the USB receiver on my new computer I some times gets a speech box (from bottom right of screen) saying “A problem occurred installing new hardware. This device may not work correctly”
At 46 I see myself lucky to have a full head of hair, this may not last long as this problem is making me PULL it out. If anyone has some advice that would help, I would be eternally grateful.
Thanks Gary.
Sorry guys Am I posting in the wrong fourum?
Should I post else where?
GaryDo other USB devices work with your computer?

Have you checked the batteries?

There is usually a small button on the bottom of the mouse that you need to press to set it to communicate with the receiver. It will be very small and probably recessed . You have to depress it with the tip of a pencil or a straightened paperclip. Have you tried resetting that?Sorry JJ I did not state these facts.
They are the more obviouse ones.
I have been using the Key board and Mouse for over 3 years (with my old comp) and have always checked the BASICS out when I have problems.
This problem seems a bit deeper than your basic problems and is more confusing for me in that I had them working with my new computer for a couple of weeks.
Also as I said they work well when I attach them to my Laptop.
Thanks for your input GaryAre you sure the drivers were for XP ? ?
One thing you can try:
Travel to Device Manager.
Right click ALL instances of USB roots and hubs and select remove/uninstall.
You will recieve a warning...ignore it.
Upon re-boot they will automatically be re-installed.
See if they work now...

If not you may want to try re-installing the MBoard drivers from the Gigabyte driver CD.Thanks Patio I will try TONIGHT when I get home from work.
I will be sure to let you Know.
Thanks Gary